Professor of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine

Speciality Interests

Neonatology, perinatology,mesenchymal stem cell(MSC), MSC derived Extracellular vesicle,neuroscience

Schedule

schedule of week
01 FRI
03
MON
06
TUE
07
WEN
08
THU
09
AM available
PM

Medical School

1994~1997 Ph.D.Seoul National University College of Medicine, Korea 1992~1994 M.S.Seoul National University College of Medicine, Korea 1983~1989 M.D.Seoul National University College of Medicine, Korea

Specialty Training

Specialty Training
Fellowship   1995~1996 Division of Neonatology, Samsung Medical Center, Korea
1994~1994 Division of Neonatology, Seoul National University Children's Hospital, Korea
Residency   1990~1994 Department of Pediatrics, Seoul National University Children's Hospital, Korea
Internship   1989~1990 Seoul National University Hospital, Korea

Other Education

  • 2021~Present Vice Chairman The Korean Society of Neonatlogy
    2021~Present Chief Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University School of Medicine"
    2019~Present Director Maternal and Child Intensive Care Center, Samsung Medical Center
    2019~Present Director Stem Cell & Regenerative Medicine Institute(Cell and Gene Therapy Institute as Changed name from 2021.12), Samsung Medical Center
    2019~Present Director Korean Neonatal Network(KNN)
    2018~2019 Vice Chairman Seoul and Kyungin tributary of the Korean Society of Neonatology
    2017~Present Chief Planning Committee, The Korean Society of Perinatology
    2013~2019 Chief Science Committee, Stem Cell & Regenerative Medicine Institute, Samsung Medical Center
    2013~2019 Secretary General Executive Committee, Korean Neonatal Network(KNN)
    2012~Present Professor Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University
    2010~Present Director NICU, Samsung Medical Center
    2009~2013 Director Committee for Data Collection and Statistics, The Korean Society of Neonatology
    2009~Present Professor Deparment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine"
    2003~2004 Visiting Scholar Neonatal brain disorder lab, University of California, San Francisco, USA
    2003~2009 Associate Professor Department of Pediatircs, Sungkyunkwan University School of Medicine
    1999~2003 Assistant Professor Department of Pediatircs, Sungkyunkwan University School of Medicine
    1997~1999 Instructor Department of Pediatircs, Sungkyunkwan University School of Medicine

Participation in Academic Societies
and Research

  • 2018~Present Member National Academy of Medicine of Korea
    2013~Present Member Society for Pediatric Research, USA
    2005~Present Member Society for Neuroscience, USA
    1994~Present Member The Korean Society of Perinatology
    1994~Present Member The Korean Society of Neonatology
    1992~Present Member The Korean Pediatric Society
    1989~Present Member Korean Medical Association

Thesis

  • SCI REP-UK 2024 10.1038/s41598-024-69680-1 Neonatologist staffing is related to the inter-hospital variation of risk-adjusted mortality of very low birth weight infants in Korea Lee, MH; Lee, JH; Chang, YS
    View PubMed
  • STEM CELL TRANSL MED 2024 10.1093/stcltm/szae060 Improving the future of clinical trials and translation of mesenchymal stromal cell therapies for neonatal disorders Chang, YS; Yang, M; Ahn, SY; Sung, SI; Park, WS
    View PubMed
  • RESP RES 2024 10.1186/s12931-024-02908-w Therapeutic efficacy of thrombin-preconditioned mesenchymal stromal cell-derived extracellular vesicles on Escherichia coli-induced acute lung injury in mice Bang, Y; Hwang, S; Kim, YE; Sung, DK; Yang, MS; Ahn, SY; Sung, SI; Joo, KM; Chang, YS
    View PubMed
  • BMJ OPEN 2024 10.1136/bmjopen-2023-082712 Asian Neonatal Network Collaboration (AsianNeo): a study protocol for international collaborative comparisons of health services and outcomes to improve quality of care for sick newborn infants in Asia - survey, cohort and quality improvement studies Isayama, T; Miyake, F; Rohsiswatmo, R; Dewi, R; Ozawa, Y; Tomotaki, S; Morisaki, N; Chee, SC; Neoh, SH; Imperial, MLS; Velasco, BAE; Chang, YS; Cho, SJ; Youn, Y; Quek, B; Poon, WB; Amin, Z; Jayaratne, K; Kumara, S; Lin, YJ; Chang, JH; Lin, HY; Lin, MC; Nuntnarumit, P; Ngerncham, S; Prempunpong, C; Prempraphan, P; Supapannachart, S; Kusuda, S
    View PubMed
  • SCI REP-UK 2024 10.1038/s41598-024-67674-7 Predictive factors for perinatal bacterial transmission from colonized mothers to delivered very-low-birth-weight infants: a retrospective cohort study Hwang, J; Kim, S; Kim, H; Kim, C; Kim, SH; Yang, MS; Ahn, SY; Sung, SI; Chang, YS
    View PubMed
  • J KOREAN MED SCI 2024 10.3346/jkms.2024.39.e139 Current Status and Associated Factors of Post-Hemorrhagic Hydrocephalus in Infants of 22 to 28 Weeks Gestation With Severe Intraventricular Hemorrhage in Korea: A Nationwide Cohort Yang, M; Kim, S; Sung, SI; Chang, YS; Park, WS; Ahn, SY
    View PubMed
  • SCI REP-UK 2024 10.1038/s41598-024-58977-w Long-term impact of late pulmonary hypertension requiring medication in extremely preterm infants with severe bronchopulmonary dysplasia Kim, C; Kim, S; Kim, H; Hwang, J; Kim, SH; Yang, MS; Ahn, SY; Sung, SI; Chang, YS
    View PubMed
  • BIOMEDICINES 2024 10.3390/biomedicines12030686 Mesenchymal Stem Cells Reduce the Extracellular Mitochondrial DNA-Mediated TLR9 Activation in Neonatal Hyperoxia-Induced Lung Injury Kim, YE; Ahn, SY; Sung, SI; Yang, MS; Sung, DK; Park, WS; Chang, YS
    View PubMed
  • SCI REP-UK 2024 10.1038/s41598-024-53163-4 The effect of minimizing central line days for very low birth weight infants through quality improvement Shin, J; Kang, HM; Kim, SY; Youn, YA; Choi, CW; Chang, YS
    View PubMed
  • FRONT PEDIATR 2024 10.3389/fped.2024.1336299 Contemporary fluid management, humidity, and patent ductus arteriosus management strategy for premature infants among 336 hospitals in Asia Hsieh, YC; Jeng, MJ; Lin, MC; Lin, YJ; Rohsiswatmo, R; Dewi, R; Chee, SC; Neoh, SH; Velasco, BAE; Imperial, MLS; Nuntnarumit, P; Ngerncham, S; Chang, YS; Kim, SY; Quek, B; Amin, Z; Kusuda, S; Miyake, F; Isayama, T
    View PubMed
  • J KOREAN MED SCI 2023 10.3346/jkms.2023.38.e350 Antenatal Magnesium Sulfate Is Not Associated With Improved Long-Term Neurodevelopment and Growth in Very Low Birth Weight Infants Jeon, GW; Ahn, SY; Kim, SM; Yang, M; Sung, SI; Sung, JH; Oh, SY; Roh, CR; Choi, SJ; Chang, YS
    View PubMed
  • J KOREAN MED SCI 2023 10.3346/jkms.2023.38.e372 Nationwide Long-Term Growth and Developmental Outcomes of Infants for Congenital Anomalies in the Digestive System and Abdominal Wall Defects With Surgery in Korea Lee, SM; Lee, JA; Chung, SH; Lee, JH; Shim, JW; Lim, JW; Kim, CR; Chang, YS
    View PubMed
  • INT J MOL SCI 2023 10.3390/ijms242216264 Mesenchymal Stromal Cells Primed by Toll-like Receptors 3 and 4 Enhanced Anti-Inflammatory Effects against LPS-Induced Macrophages via Extracellular Vesicles Hwang, S; Sung, DK; Kim, YE; Yang, MS; Ahn, SY; Sung, SI; Chang, YS
    View PubMed
  • CHILDREN-BASEL 2023 10.3390/children10101673 Optimal Protocols and Management of Clinical and Genomic Data Collection to Assist in the Early Diagnosis and Treatment of Multiple Congenital Anomalies Jo, HS; Yang, M; Ahn, SY; Sung, SI; Park, WS; Jang, JH; Chang, YS
    View PubMed
  • J KOREAN MED SCI 2023 10.3346/jkms.2023.38.e304 Major Congenital Anomalies in Korean Livebirths in 2013-2014: Based on the National Health Insurance Database Lee, JA; Lee, SM; Chung, SH; Lee, JH; Shim, JW; Lim, JW; Kim, CR; Chang, YS
    View PubMed
  • J CLIN MED 2023 10.3390/jcm12175712 Changes to Blood-Sampling Protocol to Reduce the Sampling Amount in Neonatal Intensive Care Units: A Quality Improvement Project Jung, N; Kim, C; Kim, H; Seo, Y; Hwang, J; Yang, M; Ahn, SY; Sung, SI; Chang, YS
    View PubMed
  • APPL MICROBIOL BIOT 2023 10.1007/s00253-023-12771-2 Loop-mediated isothermal amplification assay for screening congenital cytomegalovirus infection in newborns Park, H; Kim, DR; Shin, A; Jeong, E; Son, S; Ahn, JH; Ahn, SY; Choi, SJ; Oh, SY; Chang, YS; Kim, YJ; Kang, MH
    View PubMed
  • SCI REP-UK 2023 10.1038/s41598-023-42432-3 Variations in medical practice of retinopathy of prematurity among 8 Asian countries from an international survey Youn, YA; Kim, SY; Cho, SJ; Chang, YS; Miyake, F; Kusuda, S; Iskandar, ATP; Rohsiswatmo, R; Dewi, R; Chee, SC; Neoh, SH; Imperial, MLS; Velasco, BAE; Quek, BH; Lin, YJ; Chang, JH; Nuntnarumit, P; Ngerncham, S; Supapannachart, S; Ozawa, Y; Tomotaki, S; Prempunpong, C; Prempraphan, P; Isayama, T
    View PubMed
  • J KOREAN MED SCI 2023 10.3346/jkms.2023.38.e249 The Multifaceted Clinical Characteristics of Congenital Cytomegalovirus Infection: From Pregnancy to Long-Term Outcomes Kim, Y; Kim, YM; Kim, DR; Kim, HG; Sung, JH; Choi, SJ; Oh, SY; Kim, YJ; Chang, YS; Kim, D; Kim, JS; Moon, I; Roh, CR
    View PubMed
  • THORAX 2023 10.1136/thorax-2022-219622 Five-year follow-up of phase II trial of stromal cells for bronchopulmonary dysplasia Ahn, SY; Chang, YS; Lee, MH; Sung, S; Kim, A; Park, WS
    View PubMed
  • PEDIATR INFECT DIS J 2023 10.1097/INF.0000000000003931 Microbiologic Epidemiology of Early-onset Sepsis in Neonates Born at & GE;35 0/7 Weeks' Gestation in Korea During 2009-2018 Yoon, Y; So, H; Lee, JK; Kim, D; Jo, KJ; Kim, HH; Kim, YJ; Lee, JA; Jo, DS; Kim, YK; Park, SE; Chang, YS; Kim, YJ
    View PubMed
  • INT J MOL SCI 2023 10.3390/ijms24098256 SOCS3 Protein Mediates the Therapeutic Efficacy of Mesenchymal Stem Cells against Acute Lung Injury Kim, YE; Sung, DK; Bang, Y; Sung, SI; Yang, MS; Ahn, SY; Chang, YS
    View PubMed
  • SEMIN PERINATOL 2023 10.1016/j.semperi.2023.151726 Stem cells for neonatal brain injury-Lessons from the bench Ahn, SY; Chang, YS; Park, WS
    View PubMed
  • ANN LAB MED 2023 10.3343/alm.2023.43.2.153 Comprehensive Evaluation of the NeoBase 2 Non- derivatized MSMS Assay and Exploration of Analytes With Significantly Different Concentrations Between Term and Preterm Neonates Lee, BM; Heo, WY; Kim, JA; Lee, HS; Hwang, N; Park, HD; Sung, SI; Chang, YS; Park, WS; Lee, SY
    View PubMed
  • J CLIN MED 2023 10.3390/jcm12051805 Clinical Outcome of Ultrasound-Detected Perforated Necrotizing Enterocolitis without Radiographic Pneumoperitoneum in Very Preterm Infants Kim, MK; Jeon, TY; Kim, K; Kim, YJ; Yoo, SY; Kim, JH; Chang, YS; Lee, SH; Seo, JM; Moon, SH
    View PubMed
  • SCI REP-UK 2023 10.1038/s41598-023-29646-1 Impact of time to full enteral feeding on long-term neurodevelopment without mediating by postnatal growth failure in very-low-birth-weight-infants Yoon, SA; Lee, MH; Chang, YS
    View PubMed
  • BIOMEDICINES 2023 10.3390/biomedicines11010078 Conservative Management of Patent Ductus Arteriosus Is Feasible in the Peri-Viable Infants at 22-25 Gestational Weeks Yang, M; Chang, YS; Ahn, SY; Sung, SI; Jo, HS; Park, WS
    View PubMed
  • NEONATOLOGY 2022 10.1159/000527613 Neonatal Intensive Care Quality Level-Dependent Variations in the Survival Rate of Infants with a Birth Weight of 500 g or Less in Korea: A Nationwide Cohort Study Yang, MS; Chang, YS; Ahn, SY; Sung, SI; Park, WS
    View PubMed
  • J PEDIAT INF DIS SOC 2022 10.1093/jpids/piac118 The Prevalence of Symptomatic Congenital Cytomegalovirus Disease in Korea; A 15-Year Multicenter Study and Analysis of Big Data From National Health Insurance System Choi, SR; Kim, KR; Son, S; Kim, DS; Chang, YS; Cho, EY; Chang, MY; Kim, YK; Jo, DS; Kim, JK; Cho, HK; Park, SE; Park, KH; Kim, HM; Lee, BK; Kim, YJ
    View PubMed
  • ANTIMICROB AGENTS CH 2022 10.1128/aac.00889-22 Evolution of Fluconazole Resistance Mechanisms and Clonal Types of Candida parapsilosis Isolates from a Tertiary Care Hospital in South Korea Kim, TY; Huh, HJ; Lee, GY; Choi, MJ; Yu, HJ; Cho, SY; Chang, YS; Kim, YJ; Shin, JH; Lee, NY
    View PubMed
  • SCI REP-UK 2022 10.1038/s41598-022-22920-8 Comparison of definitions of bronchopulmonary dysplasia to reflect the long-term outcomes of extremely preterm infants Jeon, GW; Oh, M; Lee, J; Jun, YH; Chang, YS
    View PubMed
  • AM J OPHTHALMOL 2022 10.1016/j.ajo.2022.08.010 Association Between Retinopathy of Prematurity in Very-Low-Birth-Weight Infants and Neurodevelopmental Impairment Han, G; Lim, DH; Kang, D; Cho, J; Guallar, E; Chang, YS; Chung, TY; Kim, SJ; Park, WS
    View PubMed
  • INT J MOL SCI 2022 10.3390/ijms231810604 Mesenchymal Stem Cells and Formyl Peptide Receptor 2 Activity in Hyperoxia-Induced Lung Injury in Newborn Mice Kim, YE; Ahn, SY; Sung, DK; Chang, YS; Park, WS
    View PubMed
  • NEONATOLOGY 2022 10.1159/000526701 Early Discontinuation of Levothyroxine Treatment Is Safe and Feasible in Extremely Low Birth Weight Infants with Delayed Hyperthyrotropinemia Kim, JS; Chang, YS; Ahn, SY; Sung, SI; Yang, MS; Park, WS
    View PubMed
  • J KOREAN MED SCI 2022 10.3346/jkms.2022.37.e263 Serial Long-Term Growth and Neurodevelopment of Very-Low-Birth- Weight Infants: 2022 Update on the Korean Neonatal Network Jeon, GW; Lee, JH; Oh, M; Chang, YS
    View PubMed
  • J KOREAN MED SCI 2022 10.3346/jkms.2022.37.e229 Serial Short-Term Outcomes of Very- Low-Birth-Weight Infants in the Korean Neonatal Network From 2013 to 2020 Jeon, GW; Lee, JH; Oh, M; Chang, YS
    View PubMed
  • LIFE-BASEL 2022 10.3390/life12071030 Mesenchymal-Stem-Cell-Derived Extracellular Vesicles Attenuate Brain Injury in Escherichia coli Meningitis in Newborn Rats Kim, YE; Ahn, SY; Park, WS; Sung, DK; Sung, SI; Yang, MS; Chang, YS
    View PubMed
  • INT J MOL SCI 2022 10.3390/ijms23126527 Characterization of the Secretome of a Specific Cell Expressing Mutant Methionyl-tRNA Synthetase in Co-Culture Using Click Chemistry Shin, S; Lee, S; Choi, S; Park, N; Kwon, Y; Jeong, J; Ju, S; Chang, Y; Park, K; Ha, C; Lee, C
    View PubMed
  • SCI REP-UK 2022 10.1038/s41598-022-13927-2 Effect of levothyroxine supplementation in extremely low birth weight infants with transient hypothyroxinemia of prematurity Yoon, SA; Chang, YS; Yang, M; Ahn, SY; Sung, SI; Cho, HS; Park, WS
    View PubMed
  • INT J MOL SCI 2022 10.3390/ijms23126601 Intratracheal Transplantation of Mesenchymal Stem Cells Attenuates Hyperoxia-Induced Microbial Dysbiosis in the Lungs, Brain, and Gut in Newborn Rats Ahn, SY; Sung, DK; Chang, YS; Park, WS
    View PubMed
  • INT J MOL SCI 2022 10.3390/ijms23084447 Thrombin Preconditioning Improves the Therapeutic Efficacy of Mesenchymal Stem Cells in Severe Intraventricular Hemorrhage Induced Neonatal Rats Jung, SY; Kim, YE; Park, WS; Ahn, SY; Sung, DK; Sung, SI; Joo, KM; Kim, SG; Chang, YS
    View PubMed
  • BMC PEDIATR 2022 10.1186/s12887-022-03186-5 Development of necrotizing enterocolitis in full-term infants with duct dependent congenital heart disease Choi, GJ; Song, J; Kim, H; Huh, J; Kang, IS; Chang, YS; Sung, SI; Hyun, MC
    View PubMed
  • J KOREAN MED SCI 2022 10.3346/jkms.2022.37.e77 Perinatal Outcomes According to Accessibility to Maternal-Fetal and Neonatal Intensive Care Units by Region in Korea Lee, JH; Kwon, HS; Noh, YM; Shin, H; Kim, T; Lee, TH; Chang, YS
    View PubMed
  • NEONATOLOGY 2022 10.1159/000520452 Increased Risk of Meconium-Related Ileus in Extremely Premature Infants Exposed to Antenatal Magnesium Sulfate Sung, SI; Ahn, SY; Choi, SJ; Oh, SY; Roh, CR; Yang, MS; Chang, YS; Park, WS
    View PubMed
  • SCI REP-UK 2021 10.1038/s41598-021-03644-7 Definitions of bronchopulmonary dysplasia and long-term outcomes of extremely preterm infants in Korean Neonatal Network Jeon, GW; Oh, M; Chang, YS
    View PubMed
  • INT J MOL SCI 2021 10.3390/ijms222111395 BDNF-Overexpressing Engineered Mesenchymal Stem Cells Enhances Their Therapeutic Efficacy against Severe Neonatal Hypoxic Ischemic Brain Injury Ahn, SY; Sung, DK; Chang, YS; Sung, SI; Kim, YE; Kim, HJ; Lee, SM; Park, WS
    View PubMed
  • SCI REP-UK 2021 10.1038/s41598-021-99563-8 Cesarean section was not associated with mortality or morbidities advantage in very low birth weight infants: a nationwide cohort study Kim, JK; Chang, YS; Hwang, JH; Lee, MH; Park, WS
    View PubMed
  • J CELL MOL MED 2021 10.1111/jcmm.16971 Preclinical assessment of thrombin-preconditioned human Wharton's jelly-derived mesenchymal stem cells for neonatal hypoxic-ischaemic brain injury Noh, JH; Jeong, JS; Park, SJ; Jung, KJ; Lee, BS; Kim, WJ; Han, JS; Cho, MK; Sung, DK; Ahn, SY; Chang, YS; Son, HY; Jeong, EJ
    View PubMed
  • SCI REP-UK 2021 10.1038/s41598-021-90769-4

    Early pulmonary hypertension is a risk factor for bronchopulmonary dysplasia-associated late pulmonary hypertension in extremely preterm infants

    Kim1, HH; Sung, SI; Yang, MS; Han, YS; Kim, HS; Ahn, SY; Jeon, GW; Chang, YS; Park, WS

    J KOREAN MED SCI 2021 10.3346/jkms.2021.36.e93

    Neonatal Outcomes according to the Latent Period from Membrane Rupture to Delivery among Extremely Preterm Infants Exposed to Preterm Premature Rupture of Membrane: a Nationwide Cohort Study

    Park1, JH; Bae, JG; Chang, YS

    STEM CELLS TRANSL MED 2021 10.1002/sctm.20-0330

    Stem cells for bronchopulmonary dysplasia in preterm infants: A randomized controlled phase II trial

    Ahn1, SY; Chang, YS; Lee, MH; Sung, SI; Lee, BS; Kim, KS; Kim, AR; Park, WS

    J KOREAN MED SCI 2021 10.3346/jkms.2021.36.e86

    Mortality and Morbidities according to Time of Birth in Extremely Low Birth Weight Infants

    Yang1, M; Ahn, SY; Jo, HS; Sung, SI; Chang, YS; Park, WS

    PEDIATR NEONATOL 2021 10.1016/j.pedneo.2020.11.007

    Mesenchymal stem cell therapy for intractable neonatal disorders

    Ahn1, SY; Park, WS; Sung, SI; Chang, YS

    FRONT PEDIATR 2020 10.3389/fped.2020.605134

    Conservative Non-intervention Approach for Hemodynamically Significant Patent Ductus Arteriosus in Extremely Preterm Infants

    Sung1, SI; Chang, YS; Ahn, SY; Jo, HS; Yang, M; Park, WS

    STEM CELLS TRANSL MED 2020 10.1002/sctm.20-0301

    Brain-derived neurotropic factor mediates neuroprotection of mesenchymal stem cell-derived extracellular vesicles against severe intraventricular hemorrhage in newborn rats

    Ahn1, SY; Sung, DK; Kim, YE; Sung, S; Chang, YS; Park, WS

    NEONATOLOGY 2020 10.1159/000506165

    A Preterm Infant with Multiple Anomalies Diagnosed with Atypical CHARGE Syndrome after a Novel CHD7 Variant Confirmed Using Whole-Genome Sequencing

    Kim1, HH; Kim, AR; Kim, NKD; Ahn, SY; Sung, SI; Park, WS; Lee, C; Chang, YS; Park, WY

    SCI REP-UK 2020 10.1038/s41598-020-76472-w

    Survival rate dependent variations in retinopathy of prematurity treatment rates in very low birth weight infants

    Park1, JH; Hwang, JH; Chang, YS; Lee, MH; Park, WS

    J CLIN MED 2020 10.3390/jcm9113393

    Fish Oil Monotherapy for Intestinal Failure-Associated Liver Disease on SMOFlipid in the Neonatal Intensive Care Unit

    Lee1, S; Sung, SI; Park, HJ; Chang, YS; Park, WS; Seo, JM

    PLOS ONE 2020 10.1371/journal.pone.0240168

    Mortality rate-dependent variations in antenatal corticosteroid-associated outcomes in very low birth weight infants with 23-34 weeks of gestation A nationwide cohort study

    Kim1, JK; Hwang, JH; Lee, MH; Chang, YS; Park, WS

    JAMA PEDIATR 2020 10.1001/jamapediatrics.2020.1447

    Effect of Nonintervention vs Oral Ibuprofen in Patent Ductus Arteriosus in Preterm Infants A Randomized Clinical Trial

    Sung1, SI; Lee, MH; Ahn, SY; Chang, YS; Park, WS

    SCI REP-UK 2020 10.1038/s41598-020-69785-3

    Antenatal magnesium sulfate treatment and risk of necrotizing enterocolitis in preterm infants born at less than 32 weeks of gestation

    Hong1, JY; Hong, JY; Choi, YS; Kim, YM; Sung, JH; Choi, SJ; Oh, SY; Roh, CR; Kim, HS; Sung, SI; Ahn, SY; Chang, YS; Park, WS

    J MATERN-FETAL NEO M 2020 10.1080/14767058.2020.1749590

    Neonatal outcome comparisons between preterm infants with or without early pulmonary hypertension following prolonged preterm premature rupture of membranes before 25 gestational weeks in Korean Neonatal Network

    Park1, GY; Park, WS; Sung, SI; Kim, MS; Lee, MH; Jeon, GW; Kim, SS; Chang, YS

    PEDIATR INT 2020 10.1111/ped.14108

    Developing a newborn rat model of ventriculitis without concomitant bacteremia by intraventricular injection of K1 (-) Escherichia coli

    Ahn1, SY; Chang, YS; Sung, DK; Kim, YE; Park, WS

    J CLIN MED 2020 10.3390/jcm9030699

    Changes in Serum Creatinine Levels and Natural Evolution of Acute Kidney Injury with Conservative Management of Hemodynamically Significant Patent Ductus Arteriosus in Extremely Preterm Infants at 23-26 Weeks of Gestation

    Seo1, ES; Sung, SI; Ahn, SY; Chang, YS; Park, WS

    Int J Mol Sci. 2019 Jun 14;20(12). pii: E2899. doi: 10.3390/ijms20122899.

    Thrombin preconditioning boosts biogenesis of extracellular vesicles from mesenchymal stem cells and enriches their cargo contents via the protease activated receptors mediated signaling pathways

    Sung DK1, Sung SI, Ahn SY, Chang YS, Park WS

    Biochem Biophys Res Commun. 2019 Jan 22;508(4):1082-1087. doi: 10.1016/j.bbrc.2018.12.036.

    B23/Nucleophosmin promotes reconstitution of synaptic path in hippocampus after injury

    Yun T1, Ko HR, Ahn J, Jin EJ, Jo JM, Kwon IS, Cho SW, Chang YS, Park WS, Ahn JY

    Scientific reports 2019 E-pub

    Incidence and severity of transient hypothyroxinaemia of prematurity associated with survival without composite morbidities in extremely low birth weight infants

    Yoon SA1, Chang YS, Ahn SY, Sung SI, Park WS

    Sci Rep. 2019 May 2;9(1):6815. doi: 10.1038/s41598-019-43321-4.

    WKYMVm hexapeptide, a strong formyl peptide receptor 2 agonist, attenuates hyperoxia-induced lung injuries in newborn mice

    Kim YE1, Park WS, Ahn SY, Sung DK, Sung SI, Kim JH, Chang YS

    Sci Rep. 2019 May 14;9(1):7371. doi: 10.1038/s41598-019-43879-z.

    Mortality rate-dependent variations in the survival without major morbidities rate of extremely preterm infants

    Kim JK1, Chang YS, Sung SI, Park WS

    Pediatr Crit Care Med. 2019 Apr 2. doi: 10.1097/PCC.0000000000001913.

    Mortality rate-dependent variations in the timing and causes of death in extremely preterm infants born at 23-24 weeks�� gestation

    Park JH1, Chang YS, Sung S, Park WS, KNN

    Yonsei Med J. 2019 May;60(5):484-486. doi: 10.3349/ymj.

    A rare case of lethal form of prenatal onset of infantile cortical hyperostosis

    Kim ST1, Kim H, Kim HH, Lee NH, Han Y, Sung SI, Chang YS, Park WS

    Journal of Clinical Medicine 2019;8(4):e533

    Thrombin preconditioning of mesenchymal stem cells derived extracellular vesicles best accelerates cutaneous wound healing by boosting their biogenesis and enriching cargo contents

    Sung DK1, Chang YS, Sung SI, Ahn SY, Park WS

    J Korean Med Sci. 2019 Jan 28;34(5):e40. doi: 10.3346/jkms.2019.34.e40.

    Neonatal outcomes of very low birth weight infants in Korean Neonatal Network from 2013 to 2016

    Lee JH1, Noh OK, Chang YS, KNN

    PLoS One. 2019 Feb 13;14(2):e0212256. doi: 10.1371/journal.pone.0212256

    Natural evolution of ductus arteriosus with noninterventional conservative management in extremely preterm infants born at 23-28 weeks of gestation

    Sung SI1, Chang YS, Kim JS, Choi JH, Ahn SY, Park WS

    Eur Radiol. 2019 Jul;29(7):3847-3853. doi: 10.1007/s00330-018-5962-5.

    Outcome and risk factors associated with perirenal subcapsular fluid collections in extremely preterm infants with acute kidney injury

    Oh SL1, Jeon TY, Yoo SY, Sung SI, Kim HW, Chang YS, Park WS, Kim JH

    Neuroimage. 2019 Mar;188:335-346. doi: 10.1016/j

    Physical exercise enhances adult cortical plasticity in a neonatal rat model of hypoxic-ischemic injury: Evidence from BOLD-fMRI and electrophysiological recordings

    Chae SY1, Jang JH, Im GH, Jeong JH, Jung WB, Ko S, Jie H, Kim JH, Chang YS, Chung S, Kim KS, Lee JH

    NeoReviews 2019;20(4):e177-e188

    International Perspectives: Implementation of the Korean Neonatal Network

    Lee SM1, Chang YS, Park WS, KNN

    J Matern Fetal Neonatal Med. 2019 Jun;32(12):1938-1945. doi: 10.1080/14767058.2017.1421934.

    Short-term outcomes comparison between preterm infants with and without acute hypoxic respiratory failure attributable to presumed pulmonary hypoplasia after prolonged preterm premature upture of membranes before 25 gestational weeks

    Park GY1, Park WS, Yoo HS, Ahn SY, Sung SI, Kim SS, Chang YS

    J KOREAN MED SCI 2019 10.3346/jkms.2019.34.e271

    The Impact of Surgical Intervention on Neurodevelopmental Outcomes in Very Low Birth Weight Infants: a Nationwide Cohort Study in Korea

    Sung1, SI; Lee, NH; Kim, HH; Kim, HS; Han, YS; Yang, M; Ahn, SY; Chang, YS; Park, WS

    YONSEI MED J 2019 10.3349/ymj.2019.60.10.984

    Continuous Renal Replacement Therapy in Preterm Infants

    Noh1, ES; Kim, HH; Kim, HS; Han, YS; Yang, M; Ahn, SY; Sung, SI; Chang, YS; Park, WS

    BMC Pediatr 2019 10.1186/s12887-019-1730-1

    Initial and delayed thyroid-stimulating hormone elevation in extremely low-birth-weight infants

    Yoon1, SA; Chang, YS; Ahn, SY; Sung, SI; Park, WS

    NEONATOLOGY 2019 10.1159/000500270

    The Clinical Risk Index for Babies II for Prediction of Time-Dependent Mortality and Short-Term Morbidities in Very Low Birth Weight Infants

    Lee1, SM; Lee, MH; Chang, YS

    GLIA 2019 10.1002/glia.23712

    Reactive microglia and astrocytes in neonatal intraventricular hemorrhage model are blocked by mesenchymal stem cells

    Kim1, S; Kim, YE; Hong, S; Kim, KT; Sung, DK; Lee, Y; Park, WS; Chang, YS; Song, MR

    PLoS One 2019 10.1371/journal.pone.0221042

    Increased risk of refeeding syndrome-like hypophosphatemia with high initial amino acid intake in small-for-gestational-age, extremely-low-birthweight infants

    Sung1, SI; Chang, YS; Choi, JH; Ho, Y; Kim, J; Ahn, SY; Park, WS

    PLoS One 2019 10.1371/journal.pone.0221847

    Antenatal betamethasone enhanced the detrimental effects of postnatal dexamethasone on hyperoxic lung and brain injuries in newborn rats

    Kim1, YE; Park, WS; Sung, DK; Ahn, SY; Chang, YS

    SCI REP-UK 2019 10.1038/s41598-019-46108-9

    Incidence and severity of transient hypothyroxinaemia of prematurity associated with survival without composite morbidities in extremely low birth weight infants

    Yoon1, SA; Chang, YS; Ahn, SY; Sung, SI; Park, WS

    EUR RADIOL 2019 10.1007/s00330-018-5962-5

    Outcome and risk factors associated with perirenal subcapsular fluid collections in extremely preterm infants with acute kidney injury

    Oh1, SL; Jeon, TY; Yoo, SY; In Sung, S; Kim, HW; Chang, YS; Park, WS; Kim, JH

    PEDIATR CRIT CARE ME 2019 10.1097/PCC.0000000000001913

    Mortality Rate-Dependent Variations in the Timing and Causes of Death in Extremely Preterm Infants Born at 23-24 Weeks' Gestation*

    Park1, JH; Chang, YS; Sung, S; Park, WS

    J MATERN-FETAL NEO M 2019 10.1080/14767058.2017.1421934

    Short-term outcomes comparison between preterm infants with and without acute hypoxic respiratory failure attributable to presumed pulmonary hypoplasia after prolonged preterm premature rupture of membranes before 25 gestational weeks

    Park1, GY; Park, WS; Yoo, HS; Ahn, SY; Sung, SI; Kim, SS; Chang, YS

    INT J MOL SCI 2019 10.3390/ijms20122899

    Thrombin Preconditioning Boosts Biogenesis of Extracellular Vesicles from Mesenchymal Stem Cells and Enriches Their Cargo Contents via Protease-Activated Receptor-Mediated Signaling Pathways

    Sung1, DK; Sung, SI; Ahn, SY; Chang, YS; Park, WS

    YONSEI MED J 2019 10.3349/ymj.2019.60.5.484

    A Rare Case of Lethal Prenatal-Onset Infantile Cortical Hyperostosis

    Kim1, ST; Kim, H; Kim, HH; Lee, NH; Han, Y; Sung, SI; Chang, YS; Park, WS

    SCI REP-UK 2019 10.1038/s41598-019-43321-4

    WKYMVm hexapeptide, a strong formyl peptide receptor 2 agonist, attenuates hyperoxia-induced lung injuries in newborn mice

    Kim1, YE; Park, WS; Ahn, SY; Sung, DK; Sung, SI; Kim, JH; Chang, YS

    INT J MOL SCI 2019 10.3390/ijms20102477

    Thrombin Preconditioning Enhances Therapeutic Efficacy of Human Wharton's Jelly-Derived Mesenchymal Stem Cells in Severe Neonatal Hypoxic Ischemic Encephalopathy

    Kim1, YE; Sung, SI; Chang, YS; Ahn, SY; Sung, DK; Park, WS

    SCI REP-UK 2019 10.1038/s41598-019-43879-z

    Mortality rate-dependent variations in the survival without major morbidities rate of extremely preterm infants

    Kim1, JK; Chang, YS; Sung, S; Park, WS

    J CLIN MED 2019 10.3390/jcm8040533

    Thrombin Preconditioning of Extracellular Vesicles Derived from Mesenchymal Stem Cells Accelerates Cutaneous Wound Healing by Boosting Their Biogenesis and Enriching Cargo Content

    Sung1, DK; Chang, YS; Sung, SI; Ahn, SY; Park, WS

    NEUROIMAGE 2019 10.1016/j.neuroimage.2018.12.019

    Physical exercise enhances adult cortical plasticity in a neonatal rat model of hypoxic-ischemic injury: Evidence from BOLD-fMRI and electrophysiological recordings

    Chae1, SY; Jang, JH; Im, GH; Jeong, JH; Jung, WB; Ko, S; Jie, H; Kim, JH; Chang, YS; Chung, S; Kim, KS; Lee, JH

    J KOREAN MED SCI 2019 10.3346/jkms.2019.34.e40

    Neonatal Outcomes of Very Low Birth Weight Infants in Korean Neonatal Network from 2013 to 2016

    Lee1, JH; Noh, OK; Chang, YS

    PLoS One 2019 10.1371/journal.pone.0212256

    Natural evolution of ductus arteriosus with noninterventional conservative management in extremely preterm infants born at 23-28 weeks of gestation

    Sung1, SI; Chang, YS; Kim, J; Choi, JH; Ahn, SY; Park, WS

    BIOCHEM BIOPH RES CO 2019 10.1016/j.bbrc.2018.12.036

    B23/Nucleophosmin promotes reconstitution of synaptic path in hippocampus after injury

    Yun1, T; Ko, HR; Ahn, J; Jin, EJ; Jo, JM; Kwon, IS; Cho, SW; Chang, YS; Park, WS; Ahn, JY

    PLoS One. 2018 Feb 13;13(2):e0192232. doi: 10.1371/journal.pone.0192232.

    Predicting mortality in extremely low birth weight infants: Comparison between gestational age, birth weight, Apgar score, CRIB II score, initial and lowest serum albumin levels

    Park JH1, Chang YS, Ahn SY, Sung SI, Park WS

    J Korean Med Sci. 2018 Feb 26;33(9):e89. doi: 10.3346/jkms.2018.33.e89.

    Moving forward to improve safety and quality of neonatal intensive care in korea

    1,Chang YS

    Sci Rep. 2018 May 16;8(1):7665. doi: 10.1038/s41598-018-25902-x.

    Hypothermia broadens the therapeutic time window of mesenchymal stem cell transplantation for severe neonatal hypoxic ischemic encephalopathy

    Ahn SY1, Chang YS, Sung DK, Sung SI, Park WS

    BMC Pediatr. 2018 May 23;18(1):172. doi: 10.1186/s12887-018-1130-y.

    Trends in the incidence and associated factors of late-onset sepsis associated with improved survival in extremely preterm infants born at 23?26 weeks�� gestation: a retrospective study

    Kim JK1, Chang YS, Sung SI, Ahn SY, Park WS

    Stem Cells Transl Med. 2018 Dec;7(12):847-856. doi: 10.1002/sctm.17-0219.

    Mesenchymal stem cells for severe intraventricular hemorrhage in preterm infants: Phase I dose-escalation clinical trial

    Ahn SY1, Chang YS, Sung SI, Park WS

    Emerg Infect Dis. 2018 Sep;24(9):1768-1770. doi: 10.3201/eid2409.180625.

    Fluconazole-Resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 Gene, South Korea

    Choi YJ1, Kim YJ, Yong D, Byun JH, Kim TS, Chang YS, Choi MJ, Byeon SA, Won EJ, Kim SH, Shin MG, Shin JH

    Exp Mol Med. 2018 Apr 13;50(4):26. doi: 10.1038/s12276-018-0055-8.

    Vascular endothelial growth factor mediates the therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicles against neonatal hyperoxic lung injury

    Ahn SY1, Park WS, Kim YE, Sung DK, Sung SI, Ahn JY, Chang YS

    Pediatr Res. 2018 Nov;84(5):778-785. doi: 10.1038/s41390-018-0142-5.

    Mesenchymal stem cells transplantation attenuates brain injury and enhances bacterial clearance in Escherichia coli meningitis in newborn rats

    Ahn SY1, Chang YS, Kim YE, Sung SI, Sung DK, Park WS

    PLoS One. 2018 Oct 24;13(10):e0206311. doi: 10.1371/journal.pone.0206311

    Intratracheal transplantation of mesenchymal stem cells attenuates hyperoxia-induced lung injury by down-regulating, but not direct inhibiting formyl peptide receptor 1 in the newborn mice

    Kim YE1, Park WS, Ahn SY, Sung DK, Chang YS

    PLoS One. 2018 Oct 25;13(10):e0206306. doi: 10.1371/journal.pone.0206306.

    Dexamethasone does not prevent hydrocephalus after severe intraventricular hemorrhage in newborn rats

    Lee JH1, Chang YS, Ahn SY, Sung SI, Park WS

    Stem Cell Res Ther. 2018 Nov 21;9(1):326. doi: 10.1186/s13287-018-1052-5.

    Human UCB-MSCs treatment upon intraventricular hemorrhage contributes to attenuate hippocampal neuron loss and circuit damage through BDNF-CREB signaling

    Ko HR1, Ahn SY, Chang YS, Hwang IW, Yun TW, Sung DK, Sung SI, Park WS, Ahn JY

    J Korean Med Sci. 2018 Jan 15;33(3):e22. doi: 10.3346/jkms.2018.33.e22.

    The Youngest Survivor with Gestational Age of 21?/? Weeks

    Sung SI1, Ahn SY, Yoo HS, Chang YS, Park WS

    J Korean Med Sci. 2018 Oct 25;33(48):e294. doi: 10.3346/jkms.2018.33.e294.

    Two year's long-term outcomes of very low birth weight infants in korea

    1,Chang YS

    J Pediatr. 2018 Dec;203:437-441.e1. doi: 10.1016/j.jpeds.2018.07.082.

    Sharing data to accelerate medicine development and improve neonatal care: data standards and harmonized definitions.

    Costeloe K1, Turner MA, Padula MA, Shah PS, Modi N, Soll R, Haumont D, Kusuda S, G?pel W, Chang YS, Smith PB, Lui K, Davis JM, Hudson LD, International Neonatal Consortium

    J PEDIATR 2018 10.1016/j.jpeds.2018.07.082

    Sharing Data to Accelerate Medicine Development and Improve Neonatal Care: Data Standards and Harmonized Definitions

    Costeloe1, K; Turner, MA; Padula, MA; Shah, PS; Modi, N; Soll, R; Haumont, D; Kusuda, S; Gopel, W; Chang, YS; Smith, PB; Lui, K; Davis, JM; Hudson, LD

    Stem Cells Transl Med 2018 10.1002/sctm.17-0219

    Mesenchymal Stem Cells for Severe Intraventricular Hemorrhage in Preterm Infants: Phase I Dose-Escalation Clinical Trial

    Ahn1, SY; Chang, YS; Sung, SI; Park, WS

    STEM CELL RES THER 2018 10.1186/s13287-018-1052-5

    Human UCB-MSCs treatment upon intraventricular hemorrhage contributes to attenuate hippocampal neuron loss and circuit damage through BDNF-CREB signaling

    Ko1, HR; Ahn, SY; Chang, YS; Hwang, I; Yun, T; Sung, DK; Sung, SI; Park, WS; Ahn, JY

    J KOREAN MED SCI 2018 10.3346/jkms.2018.33.e294

    Two Year's Long-term Outcomes of Very Low Birth Weight Infants in Korea

    Chang1, YS

    PEDIATR RES 2018 10.1038/s41390-018-0142-5

    Mesenchymal stem cells transplantation attenuates brain injury and enhances bacterial clearance in Escherichia coli meningitis in newborn rats

    Ahn1, SY; Chang, YS; Kim, YE; Sung, SI; Sung, DK; Park, WS

    PLoS One 2018 10.1371/journal.pone.0206306

    Dexamethasone does not prevent hydrocephalus after severe intraventricular hemorrhage in newborn rats

    Lee1, JH; Chang, YS; Ahn, SY; Sung, SI; Park, WS

    PLoS One 2018 10.1371/journal.pone.0206311

    Intratracheal transplantation of mesenchymal stem cells attenuates hyperoxia-induced lung injury by down-regulating, but not direct inhibiting formyl peptide receptor 1 in the newborn mice

    Kim1, YE; Park, WS; Ahn, SY; Sung, DK; Chang, YS

    EMERG INFECT DIS 2018 10.3201/eid2409.180625

    Fluconazole-Resistant Candida parapsilosis Bloodstream Isolates with Y132F Mutation in ERG11 Gene, South Korea

    Choi1, YJ; Kim, YJ; Yong, D; Byun, JH; Kim, TS; Chang, YS; Choi, MJ; Byeon, SA; Won, EJ; Kim, SH; Shin, MG; Shin, JH

    BMC Pediatr 2018 10.1186/s12887-018-1130-y

    Trends in the incidence and associated factors of late-onset sepsis associated with improved survival in extremely preterm infants born at 23-26 weeks' gestation: a retrospective study

    Kim1, JK; Chang, YS; Sung, S; Ahn, SY; Park, WS

    SCI REP-UK 2018 10.1038/s41598-018-25902-x

    Hypothermia broadens the therapeutic time window of mesenchymal stem cell transplantation for severe neonatal hypoxic ischemic encephalopathy

    Ahn1, SY; Chang, YS; Sung, DK; Sung, SI; Park, WS

    EXP MOL MED 2018 10.1038/s12276-018-0055-8

    Vascular endothelial growth factor mediates the therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicles against neonatal hyperoxic lung injury

    Ahn1, SY; Park, WS; Kim, YE; Sung, DK; Sung, SI; Ahn, JY; Chang, YS

    PLoS One 2018 10.1371/journal.pone.0192232

    Predicting mortality in extremely low birth weight infants: Comparison between gestational age, birth weight, Apgar score, CRIB II score, initial and lowest serum albumin levels

    Park1, JH; Chang, YS; Ahn, SY; Sung, SI; Park, WS

    J KOREAN MED SCI 2018 10.3346/jkms.2018.33.e89

    Moving Forward to Improve Safety and Quality of Neonatal Intensive Care in Korea

    Chang1, YS

    PEDIATR RES 2018 10.1038/pr.2017.249

    Strategies to enhance paracrine potency of transplanted mesenchymal stem cells in intractable neonatal disorders

    Park1, WS; Ahn, SY; Sung, SI; Ahn, JY; Chang, YS

    J KOREAN MED SCI 2018 10.3346/jkms.2018.33.e22

    The Youngest Survivor with Gestational Age of 21(5/7) Weeks

    Sung1, SI; Ahn, SY; Yoo, HS; Chang, YS; Park, WS

    Pediatr Res. 2018 Jan;83(1-2):214-222. doi: 10.1038/pr.2017.249.

    Strategies to enhance paracrine potency of transplanted mesenchymal stem cells in intractable neonatal disorders

    Park WS1, Ahn SY, Sung SI, Ahn JY, Chang YS

    J Korean Med Sci. 2017 Aug;32(8):1288-1294. doi: 10.3346/jkms.2017.32.8.1288.

    Prophylactic versus Early Rescue Surfactant Treatment in Preterm Infants Born at less than 30 Weeks Gestation or with Birth Weight less than or equal 1,250 grams

    Chun JY1, Sung SI, Ho YH, Kim JS, Park GY, Yoon SA, Ahn SY, Chang YS, Park WS

    J Korean Med Sci. 2017 Aug;32(8):1295-1303. doi: 10.3346/jkms.2017.32.8.1295.

    Comparison of follow-up courses after discharge from neonatal intensive care unit between very low birth weight infants with and without home oxygen

    Kim JS1, Shim JW, Lee JH, Chang YS, For the Committee on Data Collection and Statistical Analysis, the Korean Society of Neonatology

    J Korean Med Sci. 2017 Oct;32(10):1717-1720. doi: 10.3346/jkms.2017.32.10.1717.

    MERS-CoV Infection in a pregnant woman in korea

    Jeong SY1, Sung SI, Sung JH, Ahn SY, Kang ES, Chang YS, Park WS, Kim JH

    Yonsei Med J. 2017 May;58(3):672-675. doi: 10.3349/ymj.2017.58.3.672.

    A Novel De Novo Pathogenic Variant in FOXF1 in a Newborn with Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins

    Ma Y1, Jang MA, Yoo HS, Ahn SY, Sung SI, Chang YS, Ki CS, Park WS

    J Pediatr. 2017 Jun;185:49-54.e2. doi: 10.1016/j.jpeds.2017.02.061.

    Two year follow up outcomes of premature infants enrolled in the phase 1 trial of mesenchymal stem cells transplantation for bronchopulmonary dysplasia

    Ahn SY1, Chang YS, Kim JH Sung SI, Park WS

    J KOREAN MED SCI 2017 10.3346/jkms.2017.32.10.1717

    MERS-CoV Infection in a Pregnant Woman in Korea

    Jeong1, SY; Sung, SI; Sung, JH; Ahn, SY; Kang, ES; Chang, YS; Park, WS; Kim, JH

    J KOREAN MED SCI 2017 10.3346/jkms.2017.32.8.1288

    Prophylactic versus Early Rescue Surfactant Treatment in Preterm Infants Born at Less than 30 Weeks Gestation or with Birth Weight Less than or Equal 1,250 Grams

    Chun1, J; Sung, SI; Ho, YH; Kim, J; Park, GY; Yoon, SA; Ahn, SY; Chang, YS; Park, WS

    J KOREAN MED SCI 2017 10.3346/jkms.2017.32.8.1295

    Comparison of Follow-up Courses after Discharge from Neonatal Intensive Care Unit between Very Low Birth Weight Infants with and without Home Oxygen

    Kim1, JS; Shim, JW; Lee, JH; Chang, YS

    BMB Rep. 2017 Mar;50(3):126-131.

    Neuron-specific expression of p48 Ebp1 during murine brain development and its contribution to CNS axon regeneration

    Ko HR11, Hwang I1, Ahn SY2, Chang YS3, Park WS3, Ahn JY4.

    Yonsei Med J. 2017 Mar;58(2):266-271. doi: 10.3349/ymj.2017.58.2.266.

    Stem Cell Therapy for Neonatal Disorders: Prospects and Challenges

    Chang YS1, Ahn SY, Sung S, Park WS.

    Cell Transplant. 2017 Mar 13;26(3):439-448. doi: 10.3727/096368916X694193. Epub 2016 Nov 30.

    Mesenchymal Stem Cells: The Magic Cure for Intraventricular Hemorrhage?

    Park WS1, Ahn SY, Sung SI, Ahn JY, Chang YS.

    Retina. 2017 Jan;37(1):88-96. doi: 10.1097/IAE.0000000000001125.

    OUTCOMES AFTER LASER VERSUS COMBINED LASER AND BEVACIZUMAB TREATMENT FOR TYPE 1 RETINOPATHY OF PREMATURITY IN ZONE I

    Yoon JM11, Shin DH, Kim SJ, Ham DI, Kang SW, Chang YS, Park WS.

    Cell Transplant. 2017 Jan 24;26(1):145-156. doi: 10.3727/096368916X692861. Epub 2016 Aug 16.

    Pivotal Role of Brain-Derived Neurotrophic Factor Secreted by Mesenchymal Stem Cells in Severe Intraventricular Hemorrhage in Newborn Rats

    Ahn SY1, Chang YS, Sung DK, Sung SI, Ahn JY, Park WS.

    ANNALS OF LABORATORY MEDICINE, JAN 2017, 37(1):58-62, DOI: 10.3343/alm.2017.37.1.58

    Novel Pathogenic Variant (c.580C>7) in the CPS1 Gene in a Newborn With Carbamoyl Phosphate Synthetase 1 Deficiency Identified by Whole Exome Sequencing

    Choi R1, Park HD, Yang M, Ki CS, Lee SY, Kim JW, Song J, Chang YS, Park WS

    PLoS One. 2017 Jan 23;12(1):e0170220. doi: 10.1371/journal.pone.0170220. eCollection 2017.

    Trends in Overall Mortality, and Timing and Cause of Death among Extremely Preterm Infants near the Limit of Viability

    Park JH11, Chang YS2, Sung S2, Ahn SY2, Park WS2.

    J Korean Med Sci. 2016 Mar;31(3):423-9. doi: 10.3346/jkms.2016.31.3.423. Epub 2016 Feb 17.

    Trends in Survival and Incidence of Bronchopulmonary Dysplasia in Extremely Preterm Infants at 23-26 Weeks Gestation

    Kim JK11, Chang YS2, Sung S2, Ahn SY2, Yoo HS2, Park WS2.

    Cell Microbiol. 2016 Mar;18(3):424-36. doi: 10.1111/cmi.12522. Epub 2015 Oct 27.

    Antibacterial effect of mesenchymal stem cells against Escherichia coli is mediated by secretion of beta- defensin-2 via toll- like receptor 4 signalling

    Sung DK11, Chang YS2,1, Sung SI2,1, Yoo HS2,1, Ahn SY2,1, Park WS2,1.

    Neuroimage. 2016 Feb 1;126:140-50. doi: 10.1016/j.neuroimage.2015.11.032. Epub 2015 Nov 14.

    Neuroplasticity for spontaneous functional recovery after neonatal hypoxic ischemic brain injury in rats observed by functional MRI and diffusion tensor imaging

    Jung WB11, Im GH2, Chung JJ3, Ahn SY4, Jeon TY5, Chang YS6, Park WS4, Kim JH5, Kim KS7, Lee JH8.

    J Pediatr. 2017 Mar;182:406. doi: 10.1016/j.jpeds.2016.11.009. Epub 2016 Nov 28.

    Mandatory Closure Versus Nonintervention for Patent Ductus Arteriosus in Very Preterm Infants

    Mimouni FB11, Hammerman C2.

    Pediatr Res. 2016 Sep;80(3):415-24. doi: 10.1038/pr.2016.88. Epub 2016 Apr 11.

    Intratracheal transplantation of mesenchymal stem cells simultaneously attenuates both lung and brain injuries in hyperoxic newborn rats

    Kim YE11, Park WS1,2,3, Sung DK2,3, Ahn SY2,3, Sung SI2, Yoo HS2, Chang YS1,2,3.

    Int J Cancer. 2016 Sep 15;139(6):1202-8. doi: 10.1002/ijc.30165. Epub 2016 May 17.

    Opposing roles of the two isoforms of ErbB3 binding protein 1 in human cancer cells

    Ko HR11, Chang YS2, Park WS2, Ahn JY1.

    Cell Transplant. 2016;25(6):1131-44. doi: 10.3727/096368915X689640. Epub 2015 Oct 5.

    Optimal Timing of Mesenchymal Stem Cell Therapy for Neonatal Intraventricular Hemorrhage

    Park WS11, Sung SI, Ahn SY, Sung DK, Im GH, Yoo HS, Choi SJ, Chang YS.

    Neonatology. 2016;109(4):377-83. doi: 10.1159/000444905. Epub 2016 Jun 3.

    Stem Cells for Neonatal Brain Disorders

    Ahn SY11, Chang YS, Park WS.

    J Korean Med Sci. 2015 Jul;30(7):924-31. doi: 10.3346/jkms.2015.30.7.924. Epub 2015 Jun 10.

    Effect of Prophylactic Palivizumab on Admission Due to Respiratory Syncytial Virus Infection in Former Very Low Birth Weight Infants with Bronchopulmonary Dysplasia

    Han YM11, Seo HJ2, Choi SH3, Jung YJ4, Ahn SY5, Yoo HS5, Sung SI5, Shim JW6, Lee YK7, Ko SY7, Shin SM7, Hwang JH8, Lee JH9, Choi BM10, Kim ES11, Jeon JH12, Kim SS13, Chang YS5, Park WS5.

    Ann Lab Med. 2015 Nov;35(6):578-85. doi: 10.3343/alm.2015.35.6.578.

    Dried Blood Spot Testing for Seven Steroids Using Liquid Chromatography-Tandem Mass Spectrometry With Reference Interval Determination in the Korean Population

    Kim B11, Lee MN1, Park HD1, Kim JW1, Chang YS2, Park WS2, Lee SY3.

    J Korean Med Sci. 2015 Oct;30 Suppl 1:S95-S103. doi: 10.3346/jkms.2015.30.S1.S95. Epub 2015 Oct 27.

    Use of Medical Resources by Preterm Infants Born at Less than 33 Weeks' Gestation Following Discharge from the Neonatal Intensive Care Unit in Korea

    Lee JH11, Chang YS2; Committee on Data Collection and Statistical Analysis, the Korean Society of Neonatology.

    J Korean Med Sci. 2015 Oct;30 Suppl 1:S3-S11. doi: 10.3346/jkms.2015.30.S1.S3. Epub 2015 Oct 27.

    The Korean Neonatal Network: An Overview

    Chang YS11, Park HY2, Park WS1.

    J Korean Med Sci. 2015 Oct;30 Suppl 1:S104-10. doi: 10.3346/jkms.2015.30.S1.S104. Epub 2015 Oct 27.

    Respiratory Syncytial Virus Related Readmission in Preterm Infants Less than 34 weeks' Gestation Following Discharge from a Neonatal Intensive Care Unit in Korea

    Lee JH11, Kim CS2, Chang YS3, Choi JH4; Committee on Data Collection and Statistical Analysis of the Korean Society of Neonatology.

    J Korean Med Sci. 2015 Oct;30 Suppl 1:S2

    PREFACE

    1,Chang YS.

    Cytotherapy. 2015 Aug;17(8):1025-35. doi: 10.1016/j.jcyt.2015.03.008. Epub 2015 Apr 8.

    Cell type-dependent variation in paracrine potency determines therapeutic efficacy against neonatal hyperoxic lung injury

    Ahn SY11, Chang YS2, Sung DK1, Yoo HS1, Sung SI1, Choi SJ3, Park WS4.

    PLoS One. 2015 Aug 25;10(8):e0135574. doi: 10.1371/journal.pone.0135574. eCollection 2015.

    Optimal Route for Human Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation to Protect Against Neonatal Hyperoxic Lung Injury: Gene Expression Profiles and Histopathology

    Sung DK11, Chang YS2, Ahn SY2, Sung SI1, Yoo HS1, Choi SJ3, Kim SY4, Park WS2.

    Yonsei Med J. 2015 Jul;56(4):998-1006. doi: 10.3349/ymj.2015.56.4.998.

    Prevention of Cytomegalovitus Transmission via Breast Milk in Extremely Low Birth Weight Infants

    Yoo HS11, Sung SI1, Jung YJ2, Lee MS1, Han YM1, Ahn SY1, Chang YS1, Park WS3.

    PLoS One. 2015 Jul 24;10(7):e0132919. doi: 10.1371/journal.pone.0132919. eCollection 2015.

    Optimal Route for Mesenchymal Stem Cells Transplantation after Severe Intraventricular Hemorrhage in Newborn Rats

    Ahn SY11, Chang YS1, Sung DK1, Sung SI1, Yoo HS1, Im GH2, Choi SJ3, Park WS1.

    J Korean Med Sci. 2015 May;30(5):509-13. doi: 10.3346/jkms.2015.30.5.509. Epub 2015 Apr 15.

    Stem Cell Therapy for Bronchopulmonary Dysplasia: Bench to Bedside Translation

    Ahn SY11, Chang YS1, Park WS1.

    PLoS One. 2015 Mar 27;10(3):e0120893. doi: 10.1371/journal.pone.0120893. eCollection 2015.

    Hypothermia Augments Neuroprotective Activity of Mesenchymal Stem Cells for Neonatal Hypoxic-Ischemic Encephalopathy

    Park WS11, Sung SI2, Ahn SY2, Yoo HS2, Sung DK3, Im GH3, Choi SJ4, Chang YS1.

    J AAPOS. 2014 Apr;18(2):124-8. doi: 10.1016/j.jaapos.2013.12.003.

    Risk factors and rate of progression for zone I versus zone II type 1 retinopathy of prematurity

    Shin DH11, Kong M1, Kim SJ2, Ham DI1, Kang SW1, Chang YS3, Park WS3.

    J Korean Med Sci. 2014 Apr;29(4):581-6. doi: 10.3346/jkms.2014.29.4.581. Epub 2014 Apr 1.

    The Timing of Surgical Ligation for Patent Ductus Arteriosus Is Associated with Neonatal Morbidity in Extremely Preterm Infants Born at 23-25 Weeks of Gestation

    Sung SI11, Choi SY1, Park JH1, Lee MS1, Yoo HS1, Ahn SY1, Chang YS1, Park WS1.

    J Perinat Med. 2014 Jan;42(1):121-7. doi: 10.1515/jpm-2013-0154.

    Steroid profiling for congenital adrenal hyperplasia by tandem mass spectrometry as a second-tier test reduces follow-up burdens in a tertiary care hospital: A retrospective and prospective evaluation

    Seo JY1, Park HD, Kim JW, Oh HJ, Yang JS, Chang YS, Park WS, Lee SY.

    Retina. 2014 Jan;34(1):77-82. doi: 10.1097/IAE.0b013e318296e26d.

    COMBINED INTRAVITREAL BEVACIZUMAB INJECTION AND ZONE I SPARING LASER PHOTOCOAGULATION IN PATIENTS WITH ZONE I RETINOPATHY OF PREMATURITY

    Kim J11, Kim SJ, Chang YS, Park WS.

    Am J Respir Cell Mol Biol.?2014 Sep;51(3):391-9. doi: 10.1165/rcmb.2013-0385OC.

    Critical Role of Vascular Endothelial Growth Factor Secreted by Mesenchymal Stem Cells in Hyperoxic Lung Injury

    Chang YS11,?Ahn SY,?Jeon HB,?Sung DK,?Kim ES,?Sung SI,?Yoo HS,?Choi SJ,?Oh WI,?Park WS.

    J Pediatr.?2014 May;164(5):966-972.e6. doi: 10.1016/j.jpeds.2013.12.011. Epub 2014 Feb 6.

    Mesenchymal Stem Cells for Bronchopulmonary Dysplasia: Phase 1 Dose-Escalation Clinical Trial

    Chang YS11,?Ahn SY1,?Yoo HS1,?Sung SI1,?Choi SJ2,?Oh WI2,?Park WS3.

    J Korean Med Sci. 2013 Jul;28(7):1071-6. doi: 10.3346/jkms.2013.28.7.1071.

    Quantitative in vivo detection of brain cell death after hypoxia ischemia using the lipid peak at 1.3 ppm of proton magnetic resonance spectroscopy in neonatal rats

    Ahn SY1, Yoo HS, Lee JH, Sung DK, Jung YJ, Sung SI, Lim KH, Chang YS, Lee JH, Kim KS, Park WS

    J Korean Med Sci. 2013 Mar;28(3):450-60. doi: 10.3346/jkms.2013.28.3.450.

    Permissive hyperglycemia in extremely low birth weight infants

    Yoo HS1, Ahn SY, Lee MS, Han YM, Sung SI, Chang YS, Park WS

    J Hum Genet.?2013 Nov;58(11):728-33. doi: 10.1038/jhg.2013.92. Epub 2013 Sep 5.

    High-dose enzyme replacement therapy attenuates cerebroventriculomegaly in a mouse model of mucopolysaccharidosis type II

    Ahn SY11,?Chang YS,?Sung DK,?Ko AR,?Kim CH,?Yoo DK,?Lim KH,?Sohn YB,?Jin DK,?Park WS.

    Pediatr Res.?2013 Jun;73(6):726-33. doi: 10.1038/pr.2013.51. Epub 2013 Mar 14.

    Antenatal betamethasone attenuates intrauterine infection-aggravated hyperoxia-induced lung injury in neonatal rats

    Yoo HS11,?Chang YS,?Kim JK,?Ahn SY,?Kim ES,?Sung DK,?Jeon GW,?Hwang JH,?Shim JW,?Park WS.

    Paediatr Perinat Epidemiol.?2013 Mar;27(2):216-25. doi: 10.1111/ppe.12033.

    The Impact of Neonatal Care Resources on Regional Variation in Neonatal Mortality Among Very Low Birthweight Infants in Korea

    Shim JW11,?Kim MJ,?Kim EK,?Park HK,?Song ES,?Lee SM,?Lee JH,?Jin HS,?Kim ES,?Chang YS;?Committee on Data Collection and Statistical Analysis, the Korean Society of Neonatology.

    Yonsei Med J.?2013 Mar 1;54(2):416-24. doi: 10.3349/ymj.2013.54.2.416.

    Long-Term (Postnatal Day 70) Outcome and Safe of Intratracheal Transplantation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Neonatal Hyperoxic Lung Injury

    Ahn SY11,?Chang YS,?Kim SY,?Sung DK,?Kim ES,?Rime SY,?Yu WJ,?Choi SJ,?Oh WI,?Park WS.

    Stroke.?2013 Feb;44(2):497-504. doi: 10.1161/STROKEAHA.112.679092. Epub 2013 Jan 3.

    Mesenchymal Stem Cells Prevent Hydrocephalus After Severe Intraventricular Hemorrhage

    Ahn SY11,?Chang YS,?Sung DK,?Sung SI,?Yoo HS,?Lee JH,?Oh WI,?Park WS.

    PLoS One.?2013;8(1):e52419. doi: 10.1371/journal.pone.0052419. Epub 2013 Jan 21.

    Timing of Umbilical Cord Blood Derived Mesenchymal Stem Cells Transplantation Determines Therapeutic Efficacy in the Neonatal Hyperoxic Lung Injury

    Chang YS11,?Choi SJ,?Ahn SY,?Sung DK,?Sung SI,?Yoo HS,?Oh WI,?Park WS.

    Yonsei Med J. 2012 Jul 1;53(4):765-71. doi: 10.3349/ymj.2012.53.4.765.

    Permissive hypotension in extremely low birth weight infants (��1000 gm)

    Ahn SY1, Kim ES, Kim JK, Shin JH, Sung SI, Jung JM, Chang YS, Park WS

    Pediatr Res. 2012 Sep;72(3):277-84. doi: 10.1038/pr.2012.71.

    Human umbilical cord blood-derived mesenchymal stem cell transplantation attenuates severe brain injury by permanent middle cerebral artery occlusion in newborn rats

    Kim ES1, Ahn SY, Im GH, Sung DK, Park YR, Choi SH, Choi SJ, Chang YS, Oh W, Lee JH, Park WS

    J Korean Med Sci. 2012 Dec;27(12):1556-62. doi: 10.3346/jkms.2012.27.12.1556.

    Retinopathy of prematurity in infants born before 25 Weeks Gestation in a Korean single neonatal intensive care unit: Incidence, natural history and risk factors

    Kong M1, Shin DH, Kim SJ, Ham DI, Kang SW, Chang YS, Park WS

    Yonsei Med J. 2011 Jan;52(1):65-73. doi: 10.3349/ymj.2011.52.1.65.

    Granulocyte colony stimulating factor attenuates hyperoxia-induced lung injury by down-modulating inflammatory responses in neonatal rats.

    Jeon GW1, Sung DK, Jung YJ, Koo SH, Choi SH, Chang YS, Sin JB, Park WS

    Pediatr Int. 2011 Oct;53(5):683-688. doi: 10.1111/j.1442-200X.2011.03332.x.

    Preterm infants fed nutrient-enriched formula until 6 months show improved growth and development

    Jeon GW1, Jung YJ, Koh SY, Lee YK, Kim KA, Shin SM, Kim SS, Shim JW, Chang YS, Park WS

    World J Pediatr. 2011 Nov;7(4):337-43. doi: 10.1007/s12519-011-0281-9.

    Swallowing dysfunction in very low birth weight iInfants with significant oral feeding desaturation

    Lee JH1, Chang YS, Yoo HS, Ahn SY, Seo HJ, Choi SH, Jeon GW, Koo SH, Lee KH, Park WS

    J Clin Apher. 2011;26(3):162-5. doi: 10.1002/jca.20283

    Successful therapeutic plasma exchange in a 3.2-kg body weight neonate with atypical hemolytic uremic syndrome

    Jung S1, Kang ES, Ki CS, Kim DW, Paik KH, Chang YS

    Cell Transplant. 2011;20(11-12):1843-54. doi: 10.3727/096368911X565038.

    Intratracheal transplantation of human umbilical cord blood derived mesenchymal stem cells dose-dependently attenuates hyperoxia-induced lung injury in neonatal rats

    Chang YS1, Choi SJ, Sung DK, Kim SY, Oh W, Yang YS, Park WS

    Cell Transplant. 2011 Mar 7. [Epub ahead of print]

    Intratracheal Transplantation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Dose-Dependently Attenuates Hyperoxia-Induced Lung Injury in Neonatal Rats

    Chang YS1, Choi SJ, Sung DK, Kim SY, Oh W, Yang YS, Park WS.

    Eur J Pediatr.?2011 Oct;170(10):1267-71. doi: 10.1007/s00431-011-1434-5. Epub 2011 Mar 4.

    PHOX2B mutations in patients with Ondine-Hirschsprung disease and a review of the literature

    Kwon MJ11,?Lee GH,?Lee MK,?Kim JY,?Yoo HS,?Ki CS,?Chang YS,?Kim JW,?Park WS.

    Respir Res.?2011 Aug 15;12:108. doi: 10.1186/1465-9921-12-108.

    Intratracheal transplantation of human umbilical cord blood-derived mesenchymal stem cells attenuates Escherichia coli-induced acute lung injury in mice

    Kim ES11,?Chang YS,?Choi SJ,?Kim JK,?Yoo HS,?Ahn SY,?Sung DK,?Kim SY,?Park YR,?Park WS.

    J Korean Med Sci. 2011 Apr;26(4):467-73. doi: 10.3346/jkms.2011.26.4.467. Epub 2011 Mar 28.

    Recent Trends in Neonatal Mortality in Very Low Birth Weight Korean Infants: In Comparison with Japan and the USA

    Hahn WH11, Chang JY, Chang YS, Shim KS, Bae CW.

    J Neurosci Methods. 2010 Nov 30;193(2):232-8. doi: 10.1016/j.jneumeth.2010.08.020.

    Comparative evaluation of hypoxic-ischemic brain injury by flow cytometric analysis of mitochondrial membrane potential with JC-1 in neonatal rats

    Sung DK1, Chang YS, Kang S, Song HY, Park WS, Lee BH

    Brain Res. 2010 Nov 4;1359:208-15. doi: 10.1016/j.brainres.2010.08.047.

    Cyclosporine A attenuates hypoxic-ischemic brain injury in the newborn rats

    Hwang J1, Lee JH, Lee K, Bae EJ, Sung DK, Chang YS, Park WS

    Ann Clin Lab Sci. 2009 Fall;39(4):399-404.

    Two Novel HADHB Gene Mutations in a Korean Patient

    Park H1, Kim SR, Ki C, Lee S, Chang YS, Jin D, Park WS

    Cell Transplant.?2009;18(8):869-86. doi: 10.3727/096368909X471189. Epub 2009 Apr 9.

    Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Attenuate Hyperoxia-Induced Lung Injury in Neonatal Rats

    Chang YS11,?Oh W,?Choi SJ,?Sung DK,?Kim SY,?Choi EY,?Kang S,?Jin HJ,?Yang YS,?Park WS.

    Exp?Lung?Res.?2009 Apr;35(3):234-49. doi: 10.1080/01902140802573007.

    alpha-PHENYL-N-tert-BUTYLNITRONE ATTENUATES HYPEROXIA-INDUCED LUNG INJURY BY DOWN-MODULATING INFLAMMATION IN NEONATAL RATS

    Chang YS11,?Kim YJ,?Yoo HS,?Sung DK,?Kim SY,?Kang S,?Park WS.

    Yonsei Med J. 2008 Oct 31;49(5):836-42. doi: 10.3349/ymj.2008.49.5.836.

    Granulocyte stimulating factor attenuates hypoxic-ischemic brain injury by inhibiting apoptosis in neonatal rats

    Kim BR1, Shim JW, Sung DK, Kim SS, Jeon GW, Kim MJ, Chang YS, Park WS, Choi, ES

    Yonsei Med J. 2008 Feb 29;49(1):144-50. doi: 10.3349/ymj.2008.49.1.144.

    Intratracheal administration of endotoxin atenuates hyperoxia-induced lung injury in neonatal rats

    Shim JW1, Chang YS, Park WS

    Yonsei Med J. 2008 Apr 30;49(2):265-71. doi: 10.3349/ymj.2008.49.2.265.

    Outcome Following Surgical Closure of Patent Ductus arteriosus in Very Low Birth Weight Infants at Neonatal Intensive Care Unit

    Lee GY1, Sohn YB, Kim MJ, Shim JW, Chang YS, Huh J, Kang I, Yang J, Jun T, Park PW, Park WS, Lee HJ

    J Korean Med Sci.?2008 Jun;23(3):484-91. doi: 10.3346/jkms.2008.23.3.484.

    Erythropoietin attenuates brain injury, subventricular zone expansion, and sensorimotor deficits in hypoxic-ischemic neonatal rats

    Kim SS11,?Lee KH,?Sung DK,?Shim JW,?Kim MJ,?Jeon GW,?Chang YS,?Park WS.

    Yonsei Med J. 2007 Aug 31;48(4):619-26.

    A comparison of AmBisome to amphotericin B for treatment of systemic candidiasis in very low birth weight infants

    Jeon GW1, Koo SH, Lee CH, Hwang JH, Kim SS, Lee EK, Chang YS, Park WS

    Eur J Pediatr. 2007 Aug;166(8):813-8. Epub 2006 Nov 22.

    Factors associated with immunoprophylaxis failure against vertical transmission of hepatitis B virus.

    Song Y1, Sung J, Yang S, Hoe, YH, Chang YS, Park WS

    J Korean Med Sci. 2007 Dec;22(6):1042-7.

    Erythropoietin Attenuates Hyperoxia-Induced Lung Injury by Down-modulating Inflammation in Neonatal Rats

    Lee JH1, Sung DK, Koo SH, Shin BK, Hong YS, Son CS, lee JW, Chang YS, Park WS

    Dev Neurosci. 2007;29(4-5):321-30.

    Erythropoietin enhances long-term neuroprotection and neurogenesis in neonatal stroke

    Gonzalez FF11, McQuillen P, Mu D, Chang Y, Wendland M, Vexler Z, Ferriero DM.

    J Korean Med Sci. 2006 Apr;21(2):337-41.

    Neuroprotective effect of cycloheximide on hypoxic-ischemic brain injury in neonatal rats

    Park WS1, Sung DK, Kang S, Koo SH, Kim YJ, Lee JH, Chang YS, Lee M

    J Korean Med Sci. 2006 Jun;21(3):490-4.

    Therapeutic window for cycloheximide treatment after hypoxic-ischemic braini injury in neonatal rats

    Park WS1, Sung DK, Kang S, Koo SH, Kim YJ, Lee JH, Chang YS, Lee M

    J Korean Med Sci.?2006 Dec;21(6):965-72.

    Pretreatment with N-nitro-L-arginine methyl ester improved oxygenation after inhalation of nitric oxide in newborn piglets with Escherichia coli pneumonia and sepsis

    Chang YS11,?Kang S,?Ko SY,?Park WS.

    J Korean Med Sci. 2005 Oct;20(5):870-6.

    Effects of hypertonic (7%) saline on brain injury in experimental Escherichia coli meningitis.

    Park SE1, Jeon GW, Chang YS, Choi CW, Hwang JH, Koo SH, Kim YJ, Lee JH, Park WS

    J Korean Med Sci. 2005 Apr;20(2):177-81.

    The efficacy of clinical strategies to reduce nosocomial sepsis in extremely low birth weight infants.

    Hwang JH1, Choi CW, Chang YS, Choi YH, Park WS, Shin SM, Lee M, Lee SI

    J Korean Med Sci. 2005 Aug;20(4):591-7.

    Comparison of clinical efficacy of Newfactan versus Surfacten for the treatment of respiratory distress syndrome in the newborn infants.

    Choi CW1, Hwang JH, Yoo EJ, Kim KA, Koh SY, , Lee YK, Shim JW, Lee EK, Chang W, Kim SS, Chang YS, Park WS, Shin SM

    Pediatr Res.?2005 Jul;58(1):106-11. Epub 2005 May 5.

    Erythropoietin improves functional and histological outcome in neonatal stroke

    Chang YS11,?Mu D,?Wendland M,?Sheldon RA,?Vexler ZS,?McQuillen PS,?Ferriero DM.

    J Korean Med Sci.?2005 Feb;20(1):61-4.

    In vitro and in vivo efficacy of new blue light emitting diode phototherapy compared to conventional halogen quartz phototherapy for neonatal jaundice

    Chang YS11,?Hwang JH,?Kwon HN,?Choi CW,?Ko SY,?Park WS,?Shin SM,?Lee M.

    J Korean Med Sci. 2004 Jun;19(3):413-8.

    Effects of alpha-phenyl-N-tert-butyl nitrone (PBN)on brain cell membrane function and energy metabolism during transient global cerebral hypoxia-ischemia and reoxygenation-reperfusion in newborn piglets.

    CW Choi1, JH Hwang, YS Chang, SM Shin, WS Park, M Lee

    Yonsei Med J. 2004 Feb 29;45(1):49-55.

    Factors affecting the response to inhaled nitric oxide therapy in persistent pulmonary hypertension of the newborn infants.

    SJ Hwang1, KH Lee, JH Hwang, CW Choi, JW Shim,YS Chang, WS Park

    J Korean Med Sci.?2004 Aug;19(4):514-8.

    Decreasing incidence of chronic lung disease despite the gradual reduction of postnatal dexamethasone use in very low birth weight infants

    Choi CW11,?Hwang JH,?Shim JW,?Ko SY,?Lee EK,?Kim SS,?Chang YS,?Park WS,?Shin SM.

    J Korean Med Sci. 2003 Oct;18(5):637-40.

    Detrimental effects of N-nitrio-L-arginine mety lester(L-NAME) in experimental Escherichia coli sepsis

    SS Kim1, JH Hwang, CW Choi, JW Shim, YS Chang, WS Park, CK Oh

    J Korean Med Sci. 2003 Dec;18(6):869-75.

    Effects of dopamine infusion on cerebral blood flow, brain cell membrane function and energy metabolism in experimental Escherichia coli meningitis in the newborn piglet.

    WS Park1, YS Chang, JW Shim, MJ Kim, SY Ko, SS Kim, JH Hwang, CW Choi, M Lee

    J Korean Med Sci. 2003 Dec;18(6):779-82.

    Comparison of mortality and morbidity in multiple versus singleton very low birth weight infants in a neonatal intensive care unit.

    KH Lee1, SJ Hwang, SH Kim, SH Lee, DK Yu, JH Hwang, CH Choi, JW Shim, YS Chang, WS Park

    J Korean Med Sci. 2003 Oct;18(5):663-8.

    Effects of perfuorocarbon associated high frequency oscillatory ventilation on hemodynamics and gas exchange in the newborn piglets with respiratory distress

    CW Choi1, SY Koh, YS Chang, WS Park

    J Korean Med Sci. 2003 Apr;18(2):236-41.

    Effect of MK-801 (dizocilpine) on brain cell membrane function and energy metabolism in experimental Escherichia coli meningitis in the newborn piglet

    Ko SY1, Shim JW, Kim SS, Kim MJ, Chang YS, Park WS, Shin SM, Lee M

    J Korean Med Sci. 2003 Dec;18(6):813-20.

    Combined effect of low-dose nitric oxide gas inhalation with partial liquid ventilation on hemodynamics, pulmonary function, and gas exchange in acute lung injury of newborn piglets

    CW Choi1, JH Hwang, YS Chang, WS Park

    Biol Neonate.?2002;82(1):61-5.

    Effect of 7-nitroindazole on bilirubin-induced changes in brain cell membrane function and energy metabolism in newborn piglets

    Park WS11,?Chang YS,?Lee M.

    Neurol Res. 2001 Dec;23(8):862-8.

    N(omega) -nitro-L-arginine methyl ester (L-NAME) attenuates the acute inflammatory responses and brain injury during the early phase of experimental Escherichia coli meningitis in the newborn piglet.

    WS Park1, YS Chang, M Lee

    J Korean Med Sci. 2001 Jun;16(3):335-41.

    Effect of hypothermia on brain cell membrane function and energy metabolism after transient global hypoxia-ischemia in the newborn piglet

    WS Park1, YS Chang, M Lee

    J Korean Med Sci. 2001 Feb;16(1):51-6.

    Changes in dead space/tidal volume ratio and pulmonary mechanics after surfactant replacement therapy in respiratory distress syndrome of the newborn infants.

    EH Chung1, SY Ko, IY Kim, YS Chang, WS Park

    Brain Res. 2001 May 18;901(1-2):102-8

    Effects of hyperglycemia or hypoglycemia on brain cell membrane function and energy metabolism during the immediate reoxygenation?reperfusion period after acute transient global hypoxia?ischemia in the newborn piglet

    WS Park1, YS Chang, M Lee

    Brain Res. 2001 Dec 20;922(2):276-81.

    Effect of hypothermia on bilirubin-induced alterations in brain cell membrane function and energy metabolism in newborn piglets.

    WS Park1, YS Chang, SH Chung, DW Seo, SH Hong, M Lee

    Neurochem Res. 2001 Apr;26(4):369-74.

    Effect of hypothermia on brain cell membrane function and energy metabolism in experimenatl Escherichia coli

    WS Park1, YS Chang, M Lee

    Neurol Res. 2001 Jun;23(4):410-6.

    3-Aminobenzamide, a poly (ADP-ribose) synthetase inhibitor, attenuates the acute inflammatory responses and brain injury in experimental Escherichia coli meningitis in the newborn piglet.

    WS Park1, YS Chang, M Lee

    Biol Neonate. 2001 Jul;80(1):53-9.

    7-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet

    WS Park1, YS Chang, M Lee

    J Korean Med Sci. 2000 Apr;15(2):153-8.

    Comparison of respiratory indices in predicting response to high frequency oscillatory ventilation in very low birth weight infants with respiratory distress syndrome.

    SY Ko1, YS Chang, WS Park

    J Korean Med Sci. 2000 Apr;15(2):203-10.

    Effects of decreased cerebral perfusion pressure on cerebral hemodynamics, brain cell membrane function and energy metabolism during the early phase of experimental Escherichia coli meningitis in the newborn piglet.

    WS Park1, YS Chang

    Biol Neonate. 2000 May;77(4):236-42.

    The efficacy of pentoxifylline as an anti-inflammatory agent in experimental Escherichia coli meningitis in the newborn piglet

    WS Park1, YS Chang, M Lee

    J Neurochem. 2000 Feb;74(2):763-9.

    Effect of alpha-phenyl-N-tert-butylnitrone on brain cell membrane function and energy metabolism in experimental Escherichia coli meningitis in the newborn piglet.

    WS Park1, YS Chang, M Lee

    Neurol Res. 1999 Jun;21(4):391-8.

    Effects of microbial invasion on cerebral hemodynamics and oxygenation monitored by near infrared spectroscopy in experimental Escherichia coli meningitis in the newborn piglet.

    WS Park1, YS Chang, SY Ko, MJ Kang, JM Han, M Lee

    Brain?Res.?1999 Oct 9;844(1-2):135-42.

    Effects of fasting and insulin-induced hypoglycemia on brain cell membrane function and energy metabolism during hypoxia-ischemia in newborn piglets

    Chang YS11,?Park WS,?Ko SY,?Kang MJ,?Han JM,?Lee M,?Choi J.

    Biol Neonate.?1999;75(6):377-87.

    Efficacy of anti-tumor necrosis factor-alpha antibody as an adjunctive therapy in experimental Escherichia coli meningitis in the newborn piglet

    Park WS11,?Chang YS,?Ko SY,?Kang MJ,?Han JM,?Lee M.

    Neurol Res.?1999 Mar;21(2):216-24.

    Near infrared spectroscopic monitoring of secondary cerebral energy failure after transient global hypoxia-ischemia in the newborn piglet

    Chang YS11,?Park WS,?Lee M,?Kim KS,?Shin SM,?Choi JH.

    Brain Res. 1998 Jul 6;798(1-2):195-203.

    Effect of induced hyperglycemia on brain cell membrane function and energy metabolism during the early phase of experimental meningitis in newborn piglets.

    WS Park1, YS Chang, M Lee

    Brain Res. 1998 Jul 6;798(1-2):271-80.

    Effect of hyperglycemia on brain cell membrane function and energy metabolism during hypoxia-ischemia in newborn piglets.

    YS Chang1, WS Park, M Lee, KS Kim, SM Shin, JH Choi

    J Korean Med Sci. 1998 Oct;13(5):495-9.

    Massive pulmonary hemorrhage in newborn infants successfully treated with high frequency oscillatory ventilation.

    SY Ko1, YS Chang, WS Park

    J Korean Med Sci. 1998 Oct;13(5):500-6.

    Clinical response to inhaled nitric oxide in persistent pulmonary hypertension of the newborn.

    SY Ko1, YS Chang, WS Park

    J Korean Med Sci. 1997 Oct;12(5):452-6.

    Microvillus inclusion disease in two Korean infants.

    NS Beck1, YS Chang, IS Kang, WS Park, HJ Lee, YL Suh

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    Patients' Rights and Responsibilities

    Patients' Rights

    1. Right to receive medical care

    Patients have the right to receive proper care in a safe setting without discrimination nor should their right to care be violated regardless of their gender, age, religion, social status, nationality, language, race, or physical/mental/financial status. Medical teams shall not refuse to provide care without justifiable reason.

    2. Right to be informed and to make an autonomous decision

    Patients have the right to obtain full and complete information from their medical team, to ask questions, and to determine their agreement or refusal concerning: diagnosis, treatment (purpose, plans and methods), outcomes of care (including unanticipated outcomes), discharge plan, participation in medical research studies, organ transplantation/donation, etc. Within ethical boundaries, patients may discontinue or refuse treatment, request that the medical team explain and suggest alternative treatments, and reserve the right to make their own decisions.

    3. Right to confidentiality

    Patients' rights to confidentiality regarding their physical/health status and privacy will not be violated. Patients can expect that all medical records/reports and their personal privacy will be kept confidential unless the patient has given consent or disclosure is permitted by law. To ensure their privacy, patients may be informed that Individuals not directly involved in their care may not be present and that the number of guardians accompanying patients to consultation rooms may be limited.

    4. Right to request consultation and mediation

    In the event of a medical dispute, patients may request consultation and mediation from an internal or external agency (Korea Consumer Agency, Korea Medical Dispute Mediation and Arbitration Agency).

    5. Right to have values and beliefs respected

    Patients will not be discriminated against because of their culture, religious values, or beliefs, and their rights will not be violated.

    6. Right to receive care in a safe setting

    Patients have the right to receive hospital-provided care where the patient’s medical information is protected and patient safety can be assured. In addition, patients have the right to be protected from possible dangers that can occur in a hospital and to have stability of mind and body.

    Patients' Responsibilities

    1. Responsibility to trust and respect the medical team

    Patients must accurately inform the medical team of their health condition and must trust and respect the medical team's treatment plan. Patients may be responsible for consequences that result from not following instructions.

    2. Responsibility to not use dishonest methods for medical treatment

    Patients must reveal their identity before receiving any medical care and must not use false or dishonest methods, such as seeking medical care under disguised ownership.

    3. Responsibility to abide by all hospital regulations

    Patients are expected to treat all hospital staff and other patients with courtesy and respect; to abide by all hospital rules; and to earnestly fulfill their financial obligation to the hospital. Also, patients and their family members are expected to participate in all safety regulations.