Pediatrics
Chang, Yun Sil
95 AppointmentProfessor of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine
Speciality Interests
Schedule
01 | FRI 03 |
MON 06 |
TUE 07 |
WEN 08 |
THU 09 |
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AM | available | ||||
PM |
Medical School
1994~1997 Ph.D.Seoul National University College of Medicine, Korea 1992~1994 M.S.Seoul National University College of Medicine, Korea 1983~1989 M.D.Seoul National University College of Medicine, Korea
Specialty Training
Fellowship | 1995~1996 Division of Neonatology, Samsung Medical Center, Korea 1994~1994 Division of Neonatology, Seoul National University Children's Hospital, Korea |
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Residency | 1990~1994 Department of Pediatrics, Seoul National University Children's Hospital, Korea | |
Internship | 1989~1990 Seoul National University Hospital, Korea |
Other Education
2021~Present Vice Chairman The Korean Society of Neonatlogy
2021~Present Chief Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University School of Medicine"
2019~Present Director Maternal and Child Intensive Care Center, Samsung Medical Center
2019~Present Director Stem Cell & Regenerative Medicine Institute(Cell and Gene Therapy Institute as Changed name from 2021.12), Samsung Medical Center
2019~Present Director Korean Neonatal Network(KNN)
2018~2019 Vice Chairman Seoul and Kyungin tributary of the Korean Society of Neonatology
2017~Present Chief Planning Committee, The Korean Society of Perinatology
2013~2019 Chief Science Committee, Stem Cell & Regenerative Medicine Institute, Samsung Medical Center
2013~2019 Secretary General Executive Committee, Korean Neonatal Network(KNN)
2012~Present Professor Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University
2010~Present Director NICU, Samsung Medical Center
2009~2013 Director Committee for Data Collection and Statistics, The Korean Society of Neonatology
2009~Present Professor Deparment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine"
2003~2004 Visiting Scholar Neonatal brain disorder lab, University of California, San Francisco, USA
2003~2009 Associate Professor Department of Pediatircs, Sungkyunkwan University School of Medicine
1999~2003 Assistant Professor Department of Pediatircs, Sungkyunkwan University School of Medicine
1997~1999 Instructor Department of Pediatircs, Sungkyunkwan University School of Medicine
Participation in Academic Societies
and Research
2018~Present Member National Academy of Medicine of Korea
2013~Present Member Society for Pediatric Research, USA
2005~Present Member Society for Neuroscience, USA
1994~Present Member The Korean Society of Perinatology
1994~Present Member The Korean Society of Neonatology
1992~Present Member The Korean Pediatric Society
1989~Present Member Korean Medical Association
Thesis
SCI REP-UK 2021 10.1038/s41598-021-90769-4
Early pulmonary hypertension is a risk factor for bronchopulmonary dysplasia-associated late pulmonary hypertension in extremely preterm infants
J KOREAN MED SCI 2021 10.3346/jkms.2021.36.e93
Neonatal Outcomes according to the Latent Period from Membrane Rupture to Delivery among Extremely Preterm Infants Exposed to Preterm Premature Rupture of Membrane: a Nationwide Cohort Study
STEM CELLS TRANSL MED 2021 10.1002/sctm.20-0330
Stem cells for bronchopulmonary dysplasia in preterm infants: A randomized controlled phase II trial
J KOREAN MED SCI 2021 10.3346/jkms.2021.36.e86
Mortality and Morbidities according to Time of Birth in Extremely Low Birth Weight Infants
PEDIATR NEONATOL 2021 10.1016/j.pedneo.2020.11.007
Mesenchymal stem cell therapy for intractable neonatal disorders
FRONT PEDIATR 2020 10.3389/fped.2020.605134
Conservative Non-intervention Approach for Hemodynamically Significant Patent Ductus Arteriosus in Extremely Preterm Infants
STEM CELLS TRANSL MED 2020 10.1002/sctm.20-0301
Brain-derived neurotropic factor mediates neuroprotection of mesenchymal stem cell-derived extracellular vesicles against severe intraventricular hemorrhage in newborn rats
NEONATOLOGY 2020 10.1159/000506165
A Preterm Infant with Multiple Anomalies Diagnosed with Atypical CHARGE Syndrome after a Novel CHD7 Variant Confirmed Using Whole-Genome Sequencing
SCI REP-UK 2020 10.1038/s41598-020-76472-w
Survival rate dependent variations in retinopathy of prematurity treatment rates in very low birth weight infants
J CLIN MED 2020 10.3390/jcm9113393
Fish Oil Monotherapy for Intestinal Failure-Associated Liver Disease on SMOFlipid in the Neonatal Intensive Care Unit
PLOS ONE 2020 10.1371/journal.pone.0240168
Mortality rate-dependent variations in antenatal corticosteroid-associated outcomes in very low birth weight infants with 23-34 weeks of gestation A nationwide cohort study
JAMA PEDIATR 2020 10.1001/jamapediatrics.2020.1447
Effect of Nonintervention vs Oral Ibuprofen in Patent Ductus Arteriosus in Preterm Infants A Randomized Clinical Trial
SCI REP-UK 2020 10.1038/s41598-020-69785-3
Antenatal magnesium sulfate treatment and risk of necrotizing enterocolitis in preterm infants born at less than 32 weeks of gestation
J MATERN-FETAL NEO M 2020 10.1080/14767058.2020.1749590
Neonatal outcome comparisons between preterm infants with or without early pulmonary hypertension following prolonged preterm premature rupture of membranes before 25 gestational weeks in Korean Neonatal Network
PEDIATR INT 2020 10.1111/ped.14108
Developing a newborn rat model of ventriculitis without concomitant bacteremia by intraventricular injection of K1 (-) Escherichia coli
J CLIN MED 2020 10.3390/jcm9030699
Changes in Serum Creatinine Levels and Natural Evolution of Acute Kidney Injury with Conservative Management of Hemodynamically Significant Patent Ductus Arteriosus in Extremely Preterm Infants at 23-26 Weeks of Gestation
Int J Mol Sci. 2019 Jun 14;20(12). pii: E2899. doi: 10.3390/ijms20122899.
Thrombin preconditioning boosts biogenesis of extracellular vesicles from mesenchymal stem cells and enriches their cargo contents via the protease activated receptors mediated signaling pathways
Biochem Biophys Res Commun. 2019 Jan 22;508(4):1082-1087. doi: 10.1016/j.bbrc.2018.12.036.
B23/Nucleophosmin promotes reconstitution of synaptic path in hippocampus after injury
Scientific reports 2019 E-pub
Incidence and severity of transient hypothyroxinaemia of prematurity associated with survival without composite morbidities in extremely low birth weight infants
Sci Rep. 2019 May 2;9(1):6815. doi: 10.1038/s41598-019-43321-4.
WKYMVm hexapeptide, a strong formyl peptide receptor 2 agonist, attenuates hyperoxia-induced lung injuries in newborn mice
Sci Rep. 2019 May 14;9(1):7371. doi: 10.1038/s41598-019-43879-z.
Mortality rate-dependent variations in the survival without major morbidities rate of extremely preterm infants
Pediatr Crit Care Med. 2019 Apr 2. doi: 10.1097/PCC.0000000000001913.
Mortality rate-dependent variations in the timing and causes of death in extremely preterm infants born at 23-24 weeks�� gestation
Yonsei Med J. 2019 May;60(5):484-486. doi: 10.3349/ymj.
A rare case of lethal form of prenatal onset of infantile cortical hyperostosis
Journal of Clinical Medicine 2019;8(4):e533
Thrombin preconditioning of mesenchymal stem cells derived extracellular vesicles best accelerates cutaneous wound healing by boosting their biogenesis and enriching cargo contents
J Korean Med Sci. 2019 Jan 28;34(5):e40. doi: 10.3346/jkms.2019.34.e40.
Neonatal outcomes of very low birth weight infants in Korean Neonatal Network from 2013 to 2016
PLoS One. 2019 Feb 13;14(2):e0212256. doi: 10.1371/journal.pone.0212256
Natural evolution of ductus arteriosus with noninterventional conservative management in extremely preterm infants born at 23-28 weeks of gestation
Eur Radiol. 2019 Jul;29(7):3847-3853. doi: 10.1007/s00330-018-5962-5.
Outcome and risk factors associated with perirenal subcapsular fluid collections in extremely preterm infants with acute kidney injury
Neuroimage. 2019 Mar;188:335-346. doi: 10.1016/j
Physical exercise enhances adult cortical plasticity in a neonatal rat model of hypoxic-ischemic injury: Evidence from BOLD-fMRI and electrophysiological recordings
NeoReviews 2019;20(4):e177-e188
International Perspectives: Implementation of the Korean Neonatal Network
J Matern Fetal Neonatal Med. 2019 Jun;32(12):1938-1945. doi: 10.1080/14767058.2017.1421934.
Short-term outcomes comparison between preterm infants with and without acute hypoxic respiratory failure attributable to presumed pulmonary hypoplasia after prolonged preterm premature upture of membranes before 25 gestational weeks
J KOREAN MED SCI 2019 10.3346/jkms.2019.34.e271
The Impact of Surgical Intervention on Neurodevelopmental Outcomes in Very Low Birth Weight Infants: a Nationwide Cohort Study in Korea
YONSEI MED J 2019 10.3349/ymj.2019.60.10.984
Continuous Renal Replacement Therapy in Preterm Infants
BMC Pediatr 2019 10.1186/s12887-019-1730-1
Initial and delayed thyroid-stimulating hormone elevation in extremely low-birth-weight infants
NEONATOLOGY 2019 10.1159/000500270
The Clinical Risk Index for Babies II for Prediction of Time-Dependent Mortality and Short-Term Morbidities in Very Low Birth Weight Infants
GLIA 2019 10.1002/glia.23712
Reactive microglia and astrocytes in neonatal intraventricular hemorrhage model are blocked by mesenchymal stem cells
PLoS One 2019 10.1371/journal.pone.0221042
Increased risk of refeeding syndrome-like hypophosphatemia with high initial amino acid intake in small-for-gestational-age, extremely-low-birthweight infants
PLoS One 2019 10.1371/journal.pone.0221847
Antenatal betamethasone enhanced the detrimental effects of postnatal dexamethasone on hyperoxic lung and brain injuries in newborn rats
SCI REP-UK 2019 10.1038/s41598-019-46108-9
Incidence and severity of transient hypothyroxinaemia of prematurity associated with survival without composite morbidities in extremely low birth weight infants
EUR RADIOL 2019 10.1007/s00330-018-5962-5
Outcome and risk factors associated with perirenal subcapsular fluid collections in extremely preterm infants with acute kidney injury
PEDIATR CRIT CARE ME 2019 10.1097/PCC.0000000000001913
Mortality Rate-Dependent Variations in the Timing and Causes of Death in Extremely Preterm Infants Born at 23-24 Weeks' Gestation*
J MATERN-FETAL NEO M 2019 10.1080/14767058.2017.1421934
Short-term outcomes comparison between preterm infants with and without acute hypoxic respiratory failure attributable to presumed pulmonary hypoplasia after prolonged preterm premature rupture of membranes before 25 gestational weeks
INT J MOL SCI 2019 10.3390/ijms20122899
Thrombin Preconditioning Boosts Biogenesis of Extracellular Vesicles from Mesenchymal Stem Cells and Enriches Their Cargo Contents via Protease-Activated Receptor-Mediated Signaling Pathways
YONSEI MED J 2019 10.3349/ymj.2019.60.5.484
A Rare Case of Lethal Prenatal-Onset Infantile Cortical Hyperostosis
SCI REP-UK 2019 10.1038/s41598-019-43321-4
WKYMVm hexapeptide, a strong formyl peptide receptor 2 agonist, attenuates hyperoxia-induced lung injuries in newborn mice
INT J MOL SCI 2019 10.3390/ijms20102477
Thrombin Preconditioning Enhances Therapeutic Efficacy of Human Wharton's Jelly-Derived Mesenchymal Stem Cells in Severe Neonatal Hypoxic Ischemic Encephalopathy
SCI REP-UK 2019 10.1038/s41598-019-43879-z
Mortality rate-dependent variations in the survival without major morbidities rate of extremely preterm infants
J CLIN MED 2019 10.3390/jcm8040533
Thrombin Preconditioning of Extracellular Vesicles Derived from Mesenchymal Stem Cells Accelerates Cutaneous Wound Healing by Boosting Their Biogenesis and Enriching Cargo Content
NEUROIMAGE 2019 10.1016/j.neuroimage.2018.12.019
Physical exercise enhances adult cortical plasticity in a neonatal rat model of hypoxic-ischemic injury: Evidence from BOLD-fMRI and electrophysiological recordings
J KOREAN MED SCI 2019 10.3346/jkms.2019.34.e40
Neonatal Outcomes of Very Low Birth Weight Infants in Korean Neonatal Network from 2013 to 2016
PLoS One 2019 10.1371/journal.pone.0212256
Natural evolution of ductus arteriosus with noninterventional conservative management in extremely preterm infants born at 23-28 weeks of gestation
BIOCHEM BIOPH RES CO 2019 10.1016/j.bbrc.2018.12.036
B23/Nucleophosmin promotes reconstitution of synaptic path in hippocampus after injury
PLoS One. 2018 Feb 13;13(2):e0192232. doi: 10.1371/journal.pone.0192232.
Predicting mortality in extremely low birth weight infants: Comparison between gestational age, birth weight, Apgar score, CRIB II score, initial and lowest serum albumin levels
J Korean Med Sci. 2018 Feb 26;33(9):e89. doi: 10.3346/jkms.2018.33.e89.
Moving forward to improve safety and quality of neonatal intensive care in korea
Sci Rep. 2018 May 16;8(1):7665. doi: 10.1038/s41598-018-25902-x.
Hypothermia broadens the therapeutic time window of mesenchymal stem cell transplantation for severe neonatal hypoxic ischemic encephalopathy
BMC Pediatr. 2018 May 23;18(1):172. doi: 10.1186/s12887-018-1130-y.
Trends in the incidence and associated factors of late-onset sepsis associated with improved survival in extremely preterm infants born at 23?26 weeks�� gestation: a retrospective study
Stem Cells Transl Med. 2018 Dec;7(12):847-856. doi: 10.1002/sctm.17-0219.
Mesenchymal stem cells for severe intraventricular hemorrhage in preterm infants: Phase I dose-escalation clinical trial
Emerg Infect Dis. 2018 Sep;24(9):1768-1770. doi: 10.3201/eid2409.180625.
Fluconazole-Resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 Gene, South Korea
Exp Mol Med. 2018 Apr 13;50(4):26. doi: 10.1038/s12276-018-0055-8.
Vascular endothelial growth factor mediates the therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicles against neonatal hyperoxic lung injury
Pediatr Res. 2018 Nov;84(5):778-785. doi: 10.1038/s41390-018-0142-5.
Mesenchymal stem cells transplantation attenuates brain injury and enhances bacterial clearance in Escherichia coli meningitis in newborn rats
PLoS One. 2018 Oct 24;13(10):e0206311. doi: 10.1371/journal.pone.0206311
Intratracheal transplantation of mesenchymal stem cells attenuates hyperoxia-induced lung injury by down-regulating, but not direct inhibiting formyl peptide receptor 1 in the newborn mice
PLoS One. 2018 Oct 25;13(10):e0206306. doi: 10.1371/journal.pone.0206306.
Dexamethasone does not prevent hydrocephalus after severe intraventricular hemorrhage in newborn rats
Stem Cell Res Ther. 2018 Nov 21;9(1):326. doi: 10.1186/s13287-018-1052-5.
Human UCB-MSCs treatment upon intraventricular hemorrhage contributes to attenuate hippocampal neuron loss and circuit damage through BDNF-CREB signaling
J Korean Med Sci. 2018 Jan 15;33(3):e22. doi: 10.3346/jkms.2018.33.e22.
The Youngest Survivor with Gestational Age of 21?/? Weeks
J Korean Med Sci. 2018 Oct 25;33(48):e294. doi: 10.3346/jkms.2018.33.e294.
Two year's long-term outcomes of very low birth weight infants in korea
J Pediatr. 2018 Dec;203:437-441.e1. doi: 10.1016/j.jpeds.2018.07.082.
Sharing data to accelerate medicine development and improve neonatal care: data standards and harmonized definitions.
J PEDIATR 2018 10.1016/j.jpeds.2018.07.082
Sharing Data to Accelerate Medicine Development and Improve Neonatal Care: Data Standards and Harmonized Definitions
Stem Cells Transl Med 2018 10.1002/sctm.17-0219
Mesenchymal Stem Cells for Severe Intraventricular Hemorrhage in Preterm Infants: Phase I Dose-Escalation Clinical Trial
STEM CELL RES THER 2018 10.1186/s13287-018-1052-5
Human UCB-MSCs treatment upon intraventricular hemorrhage contributes to attenuate hippocampal neuron loss and circuit damage through BDNF-CREB signaling
J KOREAN MED SCI 2018 10.3346/jkms.2018.33.e294
Two Year's Long-term Outcomes of Very Low Birth Weight Infants in Korea
PEDIATR RES 2018 10.1038/s41390-018-0142-5
Mesenchymal stem cells transplantation attenuates brain injury and enhances bacterial clearance in Escherichia coli meningitis in newborn rats
PLoS One 2018 10.1371/journal.pone.0206306
Dexamethasone does not prevent hydrocephalus after severe intraventricular hemorrhage in newborn rats
PLoS One 2018 10.1371/journal.pone.0206311
Intratracheal transplantation of mesenchymal stem cells attenuates hyperoxia-induced lung injury by down-regulating, but not direct inhibiting formyl peptide receptor 1 in the newborn mice
EMERG INFECT DIS 2018 10.3201/eid2409.180625
Fluconazole-Resistant Candida parapsilosis Bloodstream Isolates with Y132F Mutation in ERG11 Gene, South Korea
BMC Pediatr 2018 10.1186/s12887-018-1130-y
Trends in the incidence and associated factors of late-onset sepsis associated with improved survival in extremely preterm infants born at 23-26 weeks' gestation: a retrospective study
SCI REP-UK 2018 10.1038/s41598-018-25902-x
Hypothermia broadens the therapeutic time window of mesenchymal stem cell transplantation for severe neonatal hypoxic ischemic encephalopathy
EXP MOL MED 2018 10.1038/s12276-018-0055-8
Vascular endothelial growth factor mediates the therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicles against neonatal hyperoxic lung injury
PLoS One 2018 10.1371/journal.pone.0192232
Predicting mortality in extremely low birth weight infants: Comparison between gestational age, birth weight, Apgar score, CRIB II score, initial and lowest serum albumin levels
J KOREAN MED SCI 2018 10.3346/jkms.2018.33.e89
Moving Forward to Improve Safety and Quality of Neonatal Intensive Care in Korea
PEDIATR RES 2018 10.1038/pr.2017.249
Strategies to enhance paracrine potency of transplanted mesenchymal stem cells in intractable neonatal disorders
J KOREAN MED SCI 2018 10.3346/jkms.2018.33.e22
The Youngest Survivor with Gestational Age of 21(5/7) Weeks
Pediatr Res. 2018 Jan;83(1-2):214-222. doi: 10.1038/pr.2017.249.
Strategies to enhance paracrine potency of transplanted mesenchymal stem cells in intractable neonatal disorders
J Korean Med Sci. 2017 Aug;32(8):1288-1294. doi: 10.3346/jkms.2017.32.8.1288.
Prophylactic versus Early Rescue Surfactant Treatment in Preterm Infants Born at less than 30 Weeks Gestation or with Birth Weight less than or equal 1,250 grams
J Korean Med Sci. 2017 Aug;32(8):1295-1303. doi: 10.3346/jkms.2017.32.8.1295.
Comparison of follow-up courses after discharge from neonatal intensive care unit between very low birth weight infants with and without home oxygen
J Korean Med Sci. 2017 Oct;32(10):1717-1720. doi: 10.3346/jkms.2017.32.10.1717.
MERS-CoV Infection in a pregnant woman in korea
Yonsei Med J. 2017 May;58(3):672-675. doi: 10.3349/ymj.2017.58.3.672.
A Novel De Novo Pathogenic Variant in FOXF1 in a Newborn with Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins
J Pediatr. 2017 Jun;185:49-54.e2. doi: 10.1016/j.jpeds.2017.02.061.
Two year follow up outcomes of premature infants enrolled in the phase 1 trial of mesenchymal stem cells transplantation for bronchopulmonary dysplasia
J KOREAN MED SCI 2017 10.3346/jkms.2017.32.10.1717
MERS-CoV Infection in a Pregnant Woman in Korea
J KOREAN MED SCI 2017 10.3346/jkms.2017.32.8.1288
Prophylactic versus Early Rescue Surfactant Treatment in Preterm Infants Born at Less than 30 Weeks Gestation or with Birth Weight Less than or Equal 1,250 Grams
J KOREAN MED SCI 2017 10.3346/jkms.2017.32.8.1295
Comparison of Follow-up Courses after Discharge from Neonatal Intensive Care Unit between Very Low Birth Weight Infants with and without Home Oxygen
BMB Rep. 2017 Mar;50(3):126-131.
Neuron-specific expression of p48 Ebp1 during murine brain development and its contribution to CNS axon regeneration
Yonsei Med J. 2017 Mar;58(2):266-271. doi: 10.3349/ymj.2017.58.2.266.
Stem Cell Therapy for Neonatal Disorders: Prospects and Challenges
Cell Transplant. 2017 Mar 13;26(3):439-448. doi: 10.3727/096368916X694193. Epub 2016 Nov 30.
Mesenchymal Stem Cells: The Magic Cure for Intraventricular Hemorrhage?
Retina. 2017 Jan;37(1):88-96. doi: 10.1097/IAE.0000000000001125.
OUTCOMES AFTER LASER VERSUS COMBINED LASER AND BEVACIZUMAB TREATMENT FOR TYPE 1 RETINOPATHY OF PREMATURITY IN ZONE I
Cell Transplant. 2017 Jan 24;26(1):145-156. doi: 10.3727/096368916X692861. Epub 2016 Aug 16.
Pivotal Role of Brain-Derived Neurotrophic Factor Secreted by Mesenchymal Stem Cells in Severe Intraventricular Hemorrhage in Newborn Rats
ANNALS OF LABORATORY MEDICINE, JAN 2017, 37(1):58-62, DOI: 10.3343/alm.2017.37.1.58
Novel Pathogenic Variant (c.580C>7) in the CPS1 Gene in a Newborn With Carbamoyl Phosphate Synthetase 1 Deficiency Identified by Whole Exome Sequencing
PLoS One. 2017 Jan 23;12(1):e0170220. doi: 10.1371/journal.pone.0170220. eCollection 2017.
Trends in Overall Mortality, and Timing and Cause of Death among Extremely Preterm Infants near the Limit of Viability
J Korean Med Sci. 2016 Mar;31(3):423-9. doi: 10.3346/jkms.2016.31.3.423. Epub 2016 Feb 17.
Trends in Survival and Incidence of Bronchopulmonary Dysplasia in Extremely Preterm Infants at 23-26 Weeks Gestation
Cell Microbiol. 2016 Mar;18(3):424-36. doi: 10.1111/cmi.12522. Epub 2015 Oct 27.
Antibacterial effect of mesenchymal stem cells against Escherichia coli is mediated by secretion of beta- defensin-2 via toll- like receptor 4 signalling
Neuroimage. 2016 Feb 1;126:140-50. doi: 10.1016/j.neuroimage.2015.11.032. Epub 2015 Nov 14.
Neuroplasticity for spontaneous functional recovery after neonatal hypoxic ischemic brain injury in rats observed by functional MRI and diffusion tensor imaging
J Pediatr. 2017 Mar;182:406. doi: 10.1016/j.jpeds.2016.11.009. Epub 2016 Nov 28.
Mandatory Closure Versus Nonintervention for Patent Ductus Arteriosus in Very Preterm Infants
Pediatr Res. 2016 Sep;80(3):415-24. doi: 10.1038/pr.2016.88. Epub 2016 Apr 11.
Intratracheal transplantation of mesenchymal stem cells simultaneously attenuates both lung and brain injuries in hyperoxic newborn rats
Int J Cancer. 2016 Sep 15;139(6):1202-8. doi: 10.1002/ijc.30165. Epub 2016 May 17.
Opposing roles of the two isoforms of ErbB3 binding protein 1 in human cancer cells
Cell Transplant. 2016;25(6):1131-44. doi: 10.3727/096368915X689640. Epub 2015 Oct 5.
Optimal Timing of Mesenchymal Stem Cell Therapy for Neonatal Intraventricular Hemorrhage
Neonatology. 2016;109(4):377-83. doi: 10.1159/000444905. Epub 2016 Jun 3.
Stem Cells for Neonatal Brain Disorders
J Korean Med Sci. 2015 Jul;30(7):924-31. doi: 10.3346/jkms.2015.30.7.924. Epub 2015 Jun 10.
Effect of Prophylactic Palivizumab on Admission Due to Respiratory Syncytial Virus Infection in Former Very Low Birth Weight Infants with Bronchopulmonary Dysplasia
Ann Lab Med. 2015 Nov;35(6):578-85. doi: 10.3343/alm.2015.35.6.578.
Dried Blood Spot Testing for Seven Steroids Using Liquid Chromatography-Tandem Mass Spectrometry With Reference Interval Determination in the Korean Population
J Korean Med Sci. 2015 Oct;30 Suppl 1:S95-S103. doi: 10.3346/jkms.2015.30.S1.S95. Epub 2015 Oct 27.
Use of Medical Resources by Preterm Infants Born at Less than 33 Weeks' Gestation Following Discharge from the Neonatal Intensive Care Unit in Korea
J Korean Med Sci. 2015 Oct;30 Suppl 1:S3-S11. doi: 10.3346/jkms.2015.30.S1.S3. Epub 2015 Oct 27.
The Korean Neonatal Network: An Overview
J Korean Med Sci. 2015 Oct;30 Suppl 1:S104-10. doi: 10.3346/jkms.2015.30.S1.S104. Epub 2015 Oct 27.
Respiratory Syncytial Virus Related Readmission in Preterm Infants Less than 34 weeks' Gestation Following Discharge from a Neonatal Intensive Care Unit in Korea
Cytotherapy. 2015 Aug;17(8):1025-35. doi: 10.1016/j.jcyt.2015.03.008. Epub 2015 Apr 8.
Cell type-dependent variation in paracrine potency determines therapeutic efficacy against neonatal hyperoxic lung injury
PLoS One. 2015 Aug 25;10(8):e0135574. doi: 10.1371/journal.pone.0135574. eCollection 2015.
Optimal Route for Human Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation to Protect Against Neonatal Hyperoxic Lung Injury: Gene Expression Profiles and Histopathology
Yonsei Med J. 2015 Jul;56(4):998-1006. doi: 10.3349/ymj.2015.56.4.998.
Prevention of Cytomegalovitus Transmission via Breast Milk in Extremely Low Birth Weight Infants
PLoS One. 2015 Jul 24;10(7):e0132919. doi: 10.1371/journal.pone.0132919. eCollection 2015.
Optimal Route for Mesenchymal Stem Cells Transplantation after Severe Intraventricular Hemorrhage in Newborn Rats
J Korean Med Sci. 2015 May;30(5):509-13. doi: 10.3346/jkms.2015.30.5.509. Epub 2015 Apr 15.
Stem Cell Therapy for Bronchopulmonary Dysplasia: Bench to Bedside Translation
PLoS One. 2015 Mar 27;10(3):e0120893. doi: 10.1371/journal.pone.0120893. eCollection 2015.
Hypothermia Augments Neuroprotective Activity of Mesenchymal Stem Cells for Neonatal Hypoxic-Ischemic Encephalopathy
J AAPOS. 2014 Apr;18(2):124-8. doi: 10.1016/j.jaapos.2013.12.003.
Risk factors and rate of progression for zone I versus zone II type 1 retinopathy of prematurity
J Korean Med Sci. 2014 Apr;29(4):581-6. doi: 10.3346/jkms.2014.29.4.581. Epub 2014 Apr 1.
The Timing of Surgical Ligation for Patent Ductus Arteriosus Is Associated with Neonatal Morbidity in Extremely Preterm Infants Born at 23-25 Weeks of Gestation
J Perinat Med. 2014 Jan;42(1):121-7. doi: 10.1515/jpm-2013-0154.
Steroid profiling for congenital adrenal hyperplasia by tandem mass spectrometry as a second-tier test reduces follow-up burdens in a tertiary care hospital: A retrospective and prospective evaluation
Retina. 2014 Jan;34(1):77-82. doi: 10.1097/IAE.0b013e318296e26d.
COMBINED INTRAVITREAL BEVACIZUMAB INJECTION AND ZONE I SPARING LASER PHOTOCOAGULATION IN PATIENTS WITH ZONE I RETINOPATHY OF PREMATURITY
Am J Respir Cell Mol Biol.?2014 Sep;51(3):391-9. doi: 10.1165/rcmb.2013-0385OC.
Critical Role of Vascular Endothelial Growth Factor Secreted by Mesenchymal Stem Cells in Hyperoxic Lung Injury
J Pediatr.?2014 May;164(5):966-972.e6. doi: 10.1016/j.jpeds.2013.12.011. Epub 2014 Feb 6.
Mesenchymal Stem Cells for Bronchopulmonary Dysplasia: Phase 1 Dose-Escalation Clinical Trial
J Korean Med Sci. 2013 Jul;28(7):1071-6. doi: 10.3346/jkms.2013.28.7.1071.
Quantitative in vivo detection of brain cell death after hypoxia ischemia using the lipid peak at 1.3 ppm of proton magnetic resonance spectroscopy in neonatal rats
J Korean Med Sci. 2013 Mar;28(3):450-60. doi: 10.3346/jkms.2013.28.3.450.
Permissive hyperglycemia in extremely low birth weight infants
J Hum Genet.?2013 Nov;58(11):728-33. doi: 10.1038/jhg.2013.92. Epub 2013 Sep 5.
High-dose enzyme replacement therapy attenuates cerebroventriculomegaly in a mouse model of mucopolysaccharidosis type II
Pediatr Res.?2013 Jun;73(6):726-33. doi: 10.1038/pr.2013.51. Epub 2013 Mar 14.
Antenatal betamethasone attenuates intrauterine infection-aggravated hyperoxia-induced lung injury in neonatal rats
Paediatr Perinat Epidemiol.?2013 Mar;27(2):216-25. doi: 10.1111/ppe.12033.
The Impact of Neonatal Care Resources on Regional Variation in Neonatal Mortality Among Very Low Birthweight Infants in Korea
Yonsei Med J.?2013 Mar 1;54(2):416-24. doi: 10.3349/ymj.2013.54.2.416.
Long-Term (Postnatal Day 70) Outcome and Safe of Intratracheal Transplantation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Neonatal Hyperoxic Lung Injury
Stroke.?2013 Feb;44(2):497-504. doi: 10.1161/STROKEAHA.112.679092. Epub 2013 Jan 3.
Mesenchymal Stem Cells Prevent Hydrocephalus After Severe Intraventricular Hemorrhage
PLoS One.?2013;8(1):e52419. doi: 10.1371/journal.pone.0052419. Epub 2013 Jan 21.
Timing of Umbilical Cord Blood Derived Mesenchymal Stem Cells Transplantation Determines Therapeutic Efficacy in the Neonatal Hyperoxic Lung Injury
Yonsei Med J. 2012 Jul 1;53(4):765-71. doi: 10.3349/ymj.2012.53.4.765.
Permissive hypotension in extremely low birth weight infants (��1000 gm)
Pediatr Res. 2012 Sep;72(3):277-84. doi: 10.1038/pr.2012.71.
Human umbilical cord blood-derived mesenchymal stem cell transplantation attenuates severe brain injury by permanent middle cerebral artery occlusion in newborn rats
J Korean Med Sci. 2012 Dec;27(12):1556-62. doi: 10.3346/jkms.2012.27.12.1556.
Retinopathy of prematurity in infants born before 25 Weeks Gestation in a Korean single neonatal intensive care unit: Incidence, natural history and risk factors
Yonsei Med J. 2011 Jan;52(1):65-73. doi: 10.3349/ymj.2011.52.1.65.
Granulocyte colony stimulating factor attenuates hyperoxia-induced lung injury by down-modulating inflammatory responses in neonatal rats.
Pediatr Int. 2011 Oct;53(5):683-688. doi: 10.1111/j.1442-200X.2011.03332.x.
Preterm infants fed nutrient-enriched formula until 6 months show improved growth and development
World J Pediatr. 2011 Nov;7(4):337-43. doi: 10.1007/s12519-011-0281-9.
Swallowing dysfunction in very low birth weight iInfants with significant oral feeding desaturation
J Clin Apher. 2011;26(3):162-5. doi: 10.1002/jca.20283
Successful therapeutic plasma exchange in a 3.2-kg body weight neonate with atypical hemolytic uremic syndrome
Cell Transplant. 2011;20(11-12):1843-54. doi: 10.3727/096368911X565038.
Intratracheal transplantation of human umbilical cord blood derived mesenchymal stem cells dose-dependently attenuates hyperoxia-induced lung injury in neonatal rats
Cell Transplant. 2011 Mar 7. [Epub ahead of print]
Intratracheal Transplantation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Dose-Dependently Attenuates Hyperoxia-Induced Lung Injury in Neonatal Rats
Eur J Pediatr.?2011 Oct;170(10):1267-71. doi: 10.1007/s00431-011-1434-5. Epub 2011 Mar 4.
PHOX2B mutations in patients with Ondine-Hirschsprung disease and a review of the literature
Respir Res.?2011 Aug 15;12:108. doi: 10.1186/1465-9921-12-108.
Intratracheal transplantation of human umbilical cord blood-derived mesenchymal stem cells attenuates Escherichia coli-induced acute lung injury in mice
J Korean Med Sci. 2011 Apr;26(4):467-73. doi: 10.3346/jkms.2011.26.4.467. Epub 2011 Mar 28.
Recent Trends in Neonatal Mortality in Very Low Birth Weight Korean Infants: In Comparison with Japan and the USA
J Neurosci Methods. 2010 Nov 30;193(2):232-8. doi: 10.1016/j.jneumeth.2010.08.020.
Comparative evaluation of hypoxic-ischemic brain injury by flow cytometric analysis of mitochondrial membrane potential with JC-1 in neonatal rats
Brain Res. 2010 Nov 4;1359:208-15. doi: 10.1016/j.brainres.2010.08.047.
Cyclosporine A attenuates hypoxic-ischemic brain injury in the newborn rats
Ann Clin Lab Sci. 2009 Fall;39(4):399-404.
Two Novel HADHB Gene Mutations in a Korean Patient
Cell Transplant.?2009;18(8):869-86. doi: 10.3727/096368909X471189. Epub 2009 Apr 9.
Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Attenuate Hyperoxia-Induced Lung Injury in Neonatal Rats
Exp?Lung?Res.?2009 Apr;35(3):234-49. doi: 10.1080/01902140802573007.
alpha-PHENYL-N-tert-BUTYLNITRONE ATTENUATES HYPEROXIA-INDUCED LUNG INJURY BY DOWN-MODULATING INFLAMMATION IN NEONATAL RATS
Yonsei Med J. 2008 Oct 31;49(5):836-42. doi: 10.3349/ymj.2008.49.5.836.
Granulocyte stimulating factor attenuates hypoxic-ischemic brain injury by inhibiting apoptosis in neonatal rats
Yonsei Med J. 2008 Feb 29;49(1):144-50. doi: 10.3349/ymj.2008.49.1.144.
Intratracheal administration of endotoxin atenuates hyperoxia-induced lung injury in neonatal rats
Yonsei Med J. 2008 Apr 30;49(2):265-71. doi: 10.3349/ymj.2008.49.2.265.
Outcome Following Surgical Closure of Patent Ductus arteriosus in Very Low Birth Weight Infants at Neonatal Intensive Care Unit
J Korean Med Sci.?2008 Jun;23(3):484-91. doi: 10.3346/jkms.2008.23.3.484.
Erythropoietin attenuates brain injury, subventricular zone expansion, and sensorimotor deficits in hypoxic-ischemic neonatal rats
Yonsei Med J. 2007 Aug 31;48(4):619-26.
A comparison of AmBisome to amphotericin B for treatment of systemic candidiasis in very low birth weight infants
Eur J Pediatr. 2007 Aug;166(8):813-8. Epub 2006 Nov 22.
Factors associated with immunoprophylaxis failure against vertical transmission of hepatitis B virus.
J Korean Med Sci. 2007 Dec;22(6):1042-7.
Erythropoietin Attenuates Hyperoxia-Induced Lung Injury by Down-modulating Inflammation in Neonatal Rats
Dev Neurosci. 2007;29(4-5):321-30.
Erythropoietin enhances long-term neuroprotection and neurogenesis in neonatal stroke
J Korean Med Sci. 2006 Apr;21(2):337-41.
Neuroprotective effect of cycloheximide on hypoxic-ischemic brain injury in neonatal rats
J Korean Med Sci. 2006 Jun;21(3):490-4.
Therapeutic window for cycloheximide treatment after hypoxic-ischemic braini injury in neonatal rats
J Korean Med Sci.?2006 Dec;21(6):965-72.
Pretreatment with N-nitro-L-arginine methyl ester improved oxygenation after inhalation of nitric oxide in newborn piglets with Escherichia coli pneumonia and sepsis
J Korean Med Sci. 2005 Oct;20(5):870-6.
Effects of hypertonic (7%) saline on brain injury in experimental Escherichia coli meningitis.
J Korean Med Sci. 2005 Apr;20(2):177-81.
The efficacy of clinical strategies to reduce nosocomial sepsis in extremely low birth weight infants.
J Korean Med Sci. 2005 Aug;20(4):591-7.
Comparison of clinical efficacy of Newfactan versus Surfacten for the treatment of respiratory distress syndrome in the newborn infants.
Pediatr Res.?2005 Jul;58(1):106-11. Epub 2005 May 5.
Erythropoietin improves functional and histological outcome in neonatal stroke
J Korean Med Sci.?2005 Feb;20(1):61-4.
In vitro and in vivo efficacy of new blue light emitting diode phototherapy compared to conventional halogen quartz phototherapy for neonatal jaundice
J Korean Med Sci. 2004 Jun;19(3):413-8.
Effects of alpha-phenyl-N-tert-butyl nitrone (PBN)on brain cell membrane function and energy metabolism during transient global cerebral hypoxia-ischemia and reoxygenation-reperfusion in newborn piglets.
Yonsei Med J. 2004 Feb 29;45(1):49-55.
Factors affecting the response to inhaled nitric oxide therapy in persistent pulmonary hypertension of the newborn infants.
J Korean Med Sci.?2004 Aug;19(4):514-8.
Decreasing incidence of chronic lung disease despite the gradual reduction of postnatal dexamethasone use in very low birth weight infants
J Korean Med Sci. 2003 Oct;18(5):637-40.
Detrimental effects of N-nitrio-L-arginine mety lester(L-NAME) in experimental Escherichia coli sepsis
J Korean Med Sci. 2003 Dec;18(6):869-75.
Effects of dopamine infusion on cerebral blood flow, brain cell membrane function and energy metabolism in experimental Escherichia coli meningitis in the newborn piglet.
J Korean Med Sci. 2003 Dec;18(6):779-82.
Comparison of mortality and morbidity in multiple versus singleton very low birth weight infants in a neonatal intensive care unit.
J Korean Med Sci. 2003 Oct;18(5):663-8.
Effects of perfuorocarbon associated high frequency oscillatory ventilation on hemodynamics and gas exchange in the newborn piglets with respiratory distress
J Korean Med Sci. 2003 Apr;18(2):236-41.
Effect of MK-801 (dizocilpine) on brain cell membrane function and energy metabolism in experimental Escherichia coli meningitis in the newborn piglet
J Korean Med Sci. 2003 Dec;18(6):813-20.
Combined effect of low-dose nitric oxide gas inhalation with partial liquid ventilation on hemodynamics, pulmonary function, and gas exchange in acute lung injury of newborn piglets
Biol Neonate.?2002;82(1):61-5.
Effect of 7-nitroindazole on bilirubin-induced changes in brain cell membrane function and energy metabolism in newborn piglets
Neurol Res. 2001 Dec;23(8):862-8.
N(omega) -nitro-L-arginine methyl ester (L-NAME) attenuates the acute inflammatory responses and brain injury during the early phase of experimental Escherichia coli meningitis in the newborn piglet.
J Korean Med Sci. 2001 Jun;16(3):335-41.
Effect of hypothermia on brain cell membrane function and energy metabolism after transient global hypoxia-ischemia in the newborn piglet
J Korean Med Sci. 2001 Feb;16(1):51-6.
Changes in dead space/tidal volume ratio and pulmonary mechanics after surfactant replacement therapy in respiratory distress syndrome of the newborn infants.
Brain Res. 2001 May 18;901(1-2):102-8
Effects of hyperglycemia or hypoglycemia on brain cell membrane function and energy metabolism during the immediate reoxygenation?reperfusion period after acute transient global hypoxia?ischemia in the newborn piglet
Brain Res. 2001 Dec 20;922(2):276-81.
Effect of hypothermia on bilirubin-induced alterations in brain cell membrane function and energy metabolism in newborn piglets.
Neurochem Res. 2001 Apr;26(4):369-74.
Effect of hypothermia on brain cell membrane function and energy metabolism in experimenatl Escherichia coli
Neurol Res. 2001 Jun;23(4):410-6.
3-Aminobenzamide, a poly (ADP-ribose) synthetase inhibitor, attenuates the acute inflammatory responses and brain injury in experimental Escherichia coli meningitis in the newborn piglet.
Biol Neonate. 2001 Jul;80(1):53-9.
7-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet
J Korean Med Sci. 2000 Apr;15(2):153-8.
Comparison of respiratory indices in predicting response to high frequency oscillatory ventilation in very low birth weight infants with respiratory distress syndrome.
J Korean Med Sci. 2000 Apr;15(2):203-10.
Effects of decreased cerebral perfusion pressure on cerebral hemodynamics, brain cell membrane function and energy metabolism during the early phase of experimental Escherichia coli meningitis in the newborn piglet.
Biol Neonate. 2000 May;77(4):236-42.
The efficacy of pentoxifylline as an anti-inflammatory agent in experimental Escherichia coli meningitis in the newborn piglet
J Neurochem. 2000 Feb;74(2):763-9.
Effect of alpha-phenyl-N-tert-butylnitrone on brain cell membrane function and energy metabolism in experimental Escherichia coli meningitis in the newborn piglet.
Neurol Res. 1999 Jun;21(4):391-8.
Effects of microbial invasion on cerebral hemodynamics and oxygenation monitored by near infrared spectroscopy in experimental Escherichia coli meningitis in the newborn piglet.
Brain?Res.?1999 Oct 9;844(1-2):135-42.
Effects of fasting and insulin-induced hypoglycemia on brain cell membrane function and energy metabolism during hypoxia-ischemia in newborn piglets
Biol Neonate.?1999;75(6):377-87.
Efficacy of anti-tumor necrosis factor-alpha antibody as an adjunctive therapy in experimental Escherichia coli meningitis in the newborn piglet
Neurol Res.?1999 Mar;21(2):216-24.
Near infrared spectroscopic monitoring of secondary cerebral energy failure after transient global hypoxia-ischemia in the newborn piglet
Brain Res. 1998 Jul 6;798(1-2):195-203.
Effect of induced hyperglycemia on brain cell membrane function and energy metabolism during the early phase of experimental meningitis in newborn piglets.
Brain Res. 1998 Jul 6;798(1-2):271-80.
Effect of hyperglycemia on brain cell membrane function and energy metabolism during hypoxia-ischemia in newborn piglets.
J Korean Med Sci. 1998 Oct;13(5):495-9.
Massive pulmonary hemorrhage in newborn infants successfully treated with high frequency oscillatory ventilation.
J Korean Med Sci. 1998 Oct;13(5):500-6.
Clinical response to inhaled nitric oxide in persistent pulmonary hypertension of the newborn.
J Korean Med Sci. 1997 Oct;12(5):452-6.
Microvillus inclusion disease in two Korean infants.