삼성서울병원

Ko En

재활의학과 장원혁 교수

진료분야
뇌손상, 뇌졸중, 뇌종양, 파킨슨병 재활, 삼킴재활, 언어, 인지, 보톡스, 장애, 운동
진료일정 09 月
날짜
01
02
03
04
05
06
07
08
09
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
오전
오후
진료일정 10 月
날짜
01
02
03
04
05
06
07
08
09
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
오전
오후

학력

학력
2012.02 고려대학교 대학원 의학과 (박사)
2005.02 연세대학교 대학원 의학과 (석사)
2000.02 연세대학교 의과대학 의학과 졸업 (학사)

경력

경력
2015.04 ~현재 성균관대학교 의과대학 삼성서울병원 재활의학과 부교수
2014.09 ~ 2015.08 Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard medical school Research Fellow
2011.03 ~ 2015.03 성균관 의대 삼성서울병원 재활의학과 조교수
2010.03 ~ 2011.02 삼성서울병원 재활의학과 임상조교수
2009.03 ~ 2010.02 삼성서울병원 재활의학과 임상강사
2008.05 ~ 2009.02 신촌세브란스병원 재활의학과 임상강사
2005.04 ~ 2008.04 강화병원 재활의학과 과장 (공보의)
2001.03 ~ 2005.02 신촌세브란스병원 재활의학과 레지던트 과정 수료
2000.03 ~ 2001.02 신촌세브란스병원 인턴 과정 수료

연구분야

연구분야
비침습적 뇌자극을 이용한 기능 회복 촉진
뇌졸중, 뇌손상 등 뇌에 질환이 생긴 경우 운동기능, 인지기능, 언어기능 등 다양한 기능에 장애가 발생할 수 있습니다. 이러한 기능 장애를 치료하기 위해서 여러가지 재활치료 방법이 개발되어 사용되고 있으나 근본적 원인인 ‘뇌’ 자체를 직접 치료하는 방법에 대한 연구는 부족합니다. 비침습적 뇌자극은 수술적 치료없이 안전하고 효과적으로 뇌를 조절하여 뇌기능을 향상시킴으로써 다양한 기능적 호전을 기대할 수 있는 새로운 치료 방법입니다. 현재 안정성과 유효성이 입증되어 임상적으로 사용되고 있으나 그 효과가 제한적인 측면이 있습니다. 이에 본 연구는 향후 뇌신경재활분야의 선도적 미래의학으로 생각되는 비침습적 뇌자극의 치료 효과를 증진시키기 위한 연구입니다.

학회활동

학회활동
2017.01 ~ 현재 대한암재활학회 이사
2013.01 ~ 현재 한국재활승마학회 이사
2010.01 ~ 현재 World Federation for NeuroRehabilitation Membership
2010.01 ~ 현재 Society for Neuroscience Membership
2009.10 ~ 현재 대한뇌졸중학회 정회원
2009.03 ~ 현재 대한뇌기능매핑학회 정회원
2001.03 ~ 현재 대한뇌신경재활학회 이사
2001.03 ~ 현재 대한재활의학회 정회원

수상이력

수상이력
2017.11 재활의학 최우수연제상
2017.11 재활의학 학술상
2016.05 뇌졸중학회 Best Poster Presentation Award
2010.04 재활의학 우수포스터상
  • Disabil Rehabil. 2017 May;39(9):904-910. doi: 10.3109/09638288.2016.1170214. Epub 2016 May 20. Long-term functional outcomes of patients with very mild stroke: does a NIHSS score of 0 mean no disability? An interim analysis of the KOSCO study Chang WH11, Sohn MK2, Lee J3, Kim DY4, Lee SG5, Shin YI6, Oh GJ7, Lee YS8, Joo MC9, Han EY10, Kim MS9, Jang SY11, Kim JH1, Kim YH1,12.
    View PubMed
  • J Aging Phys Act. 2017 Apr;25(2):247-253. doi: 10.1123/japa.2015-0325. Epub 2016 Oct 5. Age-Related Locomotion Characteristics in Association with Balance Function in Young, Middle-Aged, and Older Adults Lee HJ1, Chang WH, Hwang SH, Choi BO, Ryu GH, Kim YH.
    View PubMed
  • Neurol Sci. 2017 Feb;38(2):241-247. doi: 10.1007/s10072-016-2749-9. Epub 2016 Oct 25. Corticospinal excitability in the non-dominant hand is affected by BDNF genotype Chang WH11, Hwang JM1, Uhm KE1, Pascual-Leone A2, Kim YH3,4.
    View PubMed
  • BMC Neurol. 2017 Jan 10;17(1):9. doi: 10.1186/s12883-016-0780-3. Factors associated with improvement or decline in cognitive function after an ischemic stroke in Korea: the Korean stroke cohort for functioning and rehabilitation (KOSCO) study Yoon JA11, Kim DY2, Sohn MK3, Lee J4, Lee SG5, Lee YS6, Han EY7, Joo MC8, Oh GJ8, Han J9, Park M1, Park KP10, Noh KH10, Chang WH11, Shin YI12,13, Kim YH14.
    View PubMed
  • Age-related differences in muscle co-activation during locomotion and their relationship with gait speed: a pilot study. Age-related differences in muscle co-activation during locomotion and their relationship with gait speed: a pilot study Lee HJ11, Chang WH1, Choi BO2, Ryu GH3, Kim YH4.
    View PubMed
  • Restor Neurol Neurosci. 2017;35(1):105-114. doi: 10.3233/RNN-160669. Dual-mode noninvasive brain stimulation over the bilateral primary motor cortices in stroke patients Cho JY11, Lee A2, Kim MS3, Park E1, Chang WH1, Shin YI4, Kim YH1,2.
    View PubMed
  • Brain Stimul. 2017 Jan - Feb;10(1):75-82. doi: 10.1016/j.brs.2016.08.005. Epub 2016 Aug 11. Effects of Bilateral Repetitive Transcranial Magnetic Stimulation on Post-Stroke Dysphagia Park E11, Kim MS2, Chang WH1, Oh SM1, Kim YK3, Lee A4, Kim YH5.
    View PubMed
  • Eur J Neurol. 2016 Nov;23(11):1658-1665. doi: 10.1111/ene.13101. Epub 2016 Jul 22. Effect of stress hyperglycemia and intensive rehabilitation therapy in non-diabetic hemorrhagic stroke: Korean Stroke Cohort for Functioning and Rehabilitation Yoon JA11,2, Kim DY3, Sohn MK4, Lee J5, Lee SG6, Lee YS7, Han EY8, Joo MC9, Oh GJ9, Han J10, Lee SW11, Park M1,2, Chang WH12, Shin YI13,14, Kim YH15.
    View PubMed
  • Restor Neurol Neurosci. 2016 Nov 22;34(6):915-923. The effects of combined repetitive transcranial magnetic stimulation and transcranial direct current stimulation on motor function in patients with stroke Kwon TG11, Park E2, Kang C1, Chang WH2, Kim YH2,3.
    View PubMed
  • JOURNAL OF REHABILITATION MEDICINE, OCT 2016, 48(9):824-828, DOI: 10.2340/16501977-2140 EFFECT OF CUMULATIVE REPETITIVE TRANS CRANIAL MAGNETIC STIMULATION ON FREEZING OF GAIT IN PATIENTS WITH ATYPICAL PARKINSONISM: A PILOT STUDY Chang WH1, Kim MS, Cho JW, Youn J, Kim YK, Kim SW, Lee A, Kim YH
    View PubMed
  • Restor Neurol Neurosci. 2016 Sep 21;34(5):747-55. doi: 10.3233/RNN-150634. Factors influencing the response to high-frequency repetitive transcranial magnetic stimulation in patients with subacute stroke Chang WH11, Uhm KE1, Shin YI2, Pascual-Leone A3, Kim YH1,4.
    View PubMed
  • Clin Neurophysiol. 2016 Aug;127(8):2892-7. doi: 10.1016/j.clinph.2016.04.001. Epub 2016 Apr 12. Optimal number of pulses as outcome measures of neuronavigated transcranial magnetic stimulation Chang WH11, Fried PJ2, Saxena S2, Jannati A2, Gomes-Osman J2, Kim YH3, Pascual-Leone A4.
    View PubMed
  • Restor Neurol Neurosci. 2015 Aug 26;34(4):635-45. doi: 10.3233/RNN-150534. Motor imagery learning across a sequence of trials in stroke patients Lee M11, Park CH2, Im CH3, Kim JH3, Kwon GH4, Kim L4, Chang WH2, Kim YH1,2.
    View PubMed
  • NeuroRehabilitation. 2016 Jun 27;39(2):253-9. doi: 10.3233/NRE-161355. Impact of central facial palsy and dysarthria on quality of life in patients with stroke: The KOSCO study Chang WH11, Sohn MK2, Lee J3, Kim DY4, Lee SG5, Shin YI6, Oh GJ7, Lee YS8, Joo MC9, Han EY10, Kim YH1,11.
    View PubMed
  • J Neurol. 2016 Jun;263(6):1166-77. doi: 10.1007/s00415-016-8119-y. Epub 2016 Apr 25. Predictors of functional level and quality of life at 6 months after a first-ever stroke: the KOSCO study Chang WH11, Sohn MK2, Lee J3, Kim DY4, Lee SG5, Shin YI6, Oh GJ7, Lee YS8, Joo MC9, Han EY10, Kang C1, Kim YH11,12.
    View PubMed
  • Restor Neurol Neurosci. 2016 Feb 24;34(3):379-87. doi: 10.3233/RNN-150593. Day/night difference in extradural cortical stimulation for motor relearning in a subacute stroke rat model Kim JY11, Sun W1, Park E2, Lee J2, Kim H1, Shin YI3, Kim YH2,4, Chang WH2.
    View PubMed
  • BMC Neurol. 2016 Mar 2;16:31. doi: 10.1186/s12883-016-0553-z. Cerebrolysin combined with rehabilitation promotes motor recovery in patients with severe motor impairment after stroke Chang WH11, Park CH2, Kim DY3, Shin YI4, Ko MH5, Lee A6, Jang SY7, Kim YH8,9.
    View PubMed
  • Yonsei Med J. 2016 Mar;57(2):490-5. doi: 10.3349/ymj.2016.57.2.490. Comparison between Steroid Injection and Stretching Exercise on the Scalene of Patients with Upper Extremity Paresthesia: Randomized Cross-Over Study Kim YW11, Yoon SY1, Park Y2, Chang WH3, Lee SC4.
    View PubMed
  • J Rehabil Med. 2016 Mar;48(3):273-9. doi: 10.2340/16501977-2053. RETURN TO WORK AFTER STROKE: THE KOSCO STUDY Chang WH11, Sohn MK, Lee J, Kim DY, Lee SG, Shin YI, Oh GJ, Lee YS, Joo MC, Han EY, Kim JH, Kim YH.
    View PubMed
  • Neuroepidemiology. 2016;46(1):24-30. doi: 10.1159/000441281. Epub 2015 Nov 26. Chronic Kidney Disease and Functional Outcomes 6 Months after Ischemic Stroke: A Prospective Multicenter Study Jang SY11, Sohn MK, Lee J, Kim DY, Lee SG, Shin YI, Oh GJ, Lee YS, Joo MC, Han EY, Chang WH, Lee A, Kim JH, Kim YH.
    View PubMed
  • Eur J Neurol. 2016 Jan;23(1):76-84. doi: 10.1111/ene.12791. Epub 2015 Jul 31. The brain-derived neurotrophic factor Val66Met polymorphism and degeneration of the corticospinal tract after stroke: a diffusion tensor imaging study Kim EJ11, Park CH2, Chang WH2, Lee A3, Kim ST4, Shin YI5, Kim YH2,3.
    View PubMed
  • PLoS One. 2015 Dec 14;10(12):e0139441. doi: 10.1371/journal.pone.0139441. eCollection 2015. Analysis of Time-Dependent Brain Network on Active and MI Tasks for Chronic Stroke Patients Kim DH11,2, Kim L1,3, Park W1,2, Chang WH4, Kim YH4, Lee SW2, Kwon GH5.
    View PubMed
  • BMJ Open. 2015 Dec 18;5(12):e008712. doi: 10.1136/bmjopen-2015-008712. Effect of obesity on functional outcomes at 6months post-stroke among elderly Koreans: a prospective multicentre study Jang SY11, Shin YI2, Kim DY3, Sohn MK4, Lee J5, Lee SG6, Oh GJ7, Lee YS8, Joo MC9, Han EY10, Chang WH11, Kang C11, Kim YH12.
    View PubMed
  • Restor Neurol Neurosci. 2015;33(5):589-96. doi: 10.3233/RNN-140445. Effects of extradural cortical stimulation on motor recovery in a rat model of subacute stroke Chang WH11, Kim H2, Sun W2, Kim JY2, Shin YI3, Kim YH1,4.
    View PubMed
  • Restor Neurol Neurosci. 2015 Aug 19;33(4):521-30. doi: 10.3233/RNN-140489. Efficacy of cumulative high-frequency rTMS on freezing of gait in Parkinson's disease Kim MS11, Hyuk Chang W1, Cho JW2, Youn J2, Kim YK1, Woong Kim S1, Kim YH1,3.
    View PubMed
  • Clin Neurophysiol. 2015 Jul;126(7):1348-53. doi: 10.1016/j.clinph.2014.09.028. Epub 2014 Oct 12. Different responses to facilitatory rTMS according to BDNF genotype Hwang JM11, Kim YH2, Yoon KJ3, Uhm KE1, Chang WH4.
    View PubMed
  • Neuroimage. 2015 Jun;113:101-10. doi: 10.1016/j.neuroimage.2015.03.033. Epub 2015 Mar 20. Which motor cortical region best predicts imagined movement Park CH11, Chang WH1, Lee M2, Kwon GH3, Kim L4, Kim ST5, Kim YH6.
    View PubMed
  • Neurosci Lett. 2015 May 6;594:117-21. doi: 10.1016/j.neulet.2015.03.053. Epub 2015 Mar 26. BDNF genotype influence the efficacy of rTMS in stroke patients Uhm KE11, Kim YH2, Yoon KJ3, Hwang JM1, Chang WH4.
    View PubMed
  • Neurorehabil Neural Repair. 2015 Mar-Apr;29(3):247-54. doi: 10.1177/1545968314543308. Epub 2014 Jul 22. Predicting the Performance of Motor Imagery in Stroke Patients: Multivariate Pattern Analysis of Functional MRI Data Park CH11, Chang WH1, Lee M2, Kwon GH3, Kim L3, Kim ST1, Kim YH4.
    View PubMed
  • BMC Neurol. 2015 Mar 25;15:42. doi: 10.1186/s12883-015-0293-5. Korean Stroke Cohort for functioning and rehabilitation (KOSCO): study rationale and protocol of a multi-centre prospective cohort study Chang WH11, Sohn MK2, Lee J3, Kim DY4, Lee SG5, Shin YI6, Oh GJ7, Lee YS8, Joo MC9, Han EY10, Kim YH11.
    View PubMed
  • Yonsei Med J.?2015 Jan;56(1):262-70. doi: 10.3349/ymj.2015.56.1.262. Characteristics of Inpatient Care and Rehabilitation for Acute First-Ever Stroke Patients Chang WH11,?Shin YI2,?Lee SG3,?Oh GJ4,?Lim YS5,?Kim YH6.
    View PubMed
  • Neurosci Lett. 2015 Jan 1;584:347-50. doi: 10.1016/j.neulet.2014.10.052. Epub 2014 Nov 3. What is the optimal anodal electrode position for inducing corticomotor excitability changes in transcranial direct current stimulation Lee M11, Kim YH2, Im CH3, Kim JH4, Park CH5, Chang WH6, Lee A7.
    View PubMed
  • Clin Neurophysiol. 2014 Dec;125(12):2397-403. doi: 10.1016/j.clinph.2014.02.025. Epub 2014 Mar 18. Changes in diffusion tensor tractographic findings associated with constraint-induced movement therapy in young children with cerebral palsy Kwon JY11, Chang WH2, Chang HJ3, Yi SH4, Kim MY1, Kim EH5, Kim YH6.
    View PubMed
  • J Phys Ther Sci. 2014 Dec;26(12):1949-53. doi: 10.1589/jpts.26.1949. Epub 2014 Dec 25. Effects of Robot-assisted Gait Training Combined with Functional Electrical Stimulation on Recovery of Locomotor Mobility in Chronic Stroke Patients: A Randomized Controlled Trial Bae YH11, Ko YJ2, Chang WH3, Lee JH4, Lee KB4, Park YJ4, Ha HG2, Kim YH3.
    View PubMed
  • Restor Neurol Neurosci. 2014;32(6):743-53. doi: 10.3233/RNN-140397. Effects of repetitive transcranial magnetic stimulation on freezing of gait in patients with Parkinsonism Lee SY11, Kim MS1, Chang WH1, Cho JW2, Youn JY2, Kim YH3.
    View PubMed
  • Rheumatol Int.?2014 Sep;34(9):1203-9. doi: 10.1007/s00296-014-2966-6. Epub 2014 Feb 20. Comparison of the therapeutic effects of intramuscular subscapularis and scapulothoracic bursa injections in patients with scapular pain: a randomized controlled trial Chang WH11,?Kim YW,?Choi S,?Lee SC.
    View PubMed
  • Eur J Neurosci. 2014 Aug;40(4):2715-22. doi: 10.1111/ejn.12640. Epub 2014 Jun 16. Significance of longitudinal changes in the default-mode network for cognitive recovery after stroke Park JY11, Kim YH, Chang WH, Park CH, Shin YI, Kim ST, Pascual-Leone A.
    View PubMed
  • Brain Stimul.?2014 Jul-Aug;7(4):553-8. doi: 10.1016/j.brs.2014.03.008. Epub 2014 Mar 26. BDNF Polymorphism and Differential rTMS Effects on Motor Recovery of Stroke Patients Chang WH11,?Bang OY2,?Shin YI3,?Lee A4,?Pascual-Leone A5,?Kim YH6.
    View PubMed
  • Neurosci Lett. 2014 May 1;567:24-9. doi: 10.1016/j.neulet.2014.03.022. Epub 2014 Mar 26. Effects of dual-mode non-invasive brain stimulation on motor function Park E11, Kim YH2, Chang WH1, Kwon TG1, Shin YI3.
    View PubMed
  • Yonsei Med J. 2014 May;55(3):792-9. doi: 10.3349/ymj.2014.55.3.792. Epub 2014 Apr 1. Application of Ultrasound-Guided Trigger Point Injection for Myofascial Trigger Points in the Subscapularis and Pectoralis Muscles to Post-Mastectomy Patients: A Pilot Study Shin HJ11, Shin JC2, Kim WS1, Chang WH3, Lee SC2.
    View PubMed
  • Neurosci Lett. 2014 Apr 3;564:6-10. doi: 10.1016/j.neulet.2014.01.054. Epub 2014 Feb 6. Inconsistent outcomes of transcranial direct current stimulation may originate from anatomical differences among individuals: Electric field simulation using individual MRI data Kim JH11, Kim DW1, Chang WH2, Kim YH2, Kim K3, Im CH4.
    View PubMed
  • Restor Neurol Neurosci. 2014;32(2):223-32. doi: 10.3233/RNN-130313. Effective method of combining rTMS and motor training in stroke patients Kwon TG11, Kim YH2, Chang WH1, Bang OY3, Shin YI4.
    View PubMed
  • Arch Phys Med Rehabil. 2013 Aug;94(8):1580-3. doi: 10.1016/j.apmr.2012.11.006. Epub 2012 Nov 12. Correlation Between Voluntary Cough and Laryngeal Cough Reflex Flows in Patients With Traumatic Brain Injury Lee SC11, Kang SW, Kim MT, Kim YK, Chang WH, Im SH.
    View PubMed
  • Arch Phys Med Rehabil. 2013 May;94(5):930-6. doi: 10.1016/j.apmr.2012.12.011. Epub 2012 Dec 21. Usefulness of a Myofascial Trigger Point Injection for Groin Pain in Patients With Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Study Kim DS11, Jeong TY, Kim YK, Chang WH, Yoon JG, Lee SC.
    View PubMed
  • Neuroradiology. 2012 Jun;54(6):615-21. doi: 10.1007/s00234-011-0996-2. Epub 2011 Dec 16. Comparing quantitative tractography metrics of motor and sensory pathways in children with periventricular leukomalacia and different levels of gross motor function Rha DW11, Chang WH, Kim J, Sim EG, Park ES.
    View PubMed
  • Neurorehabil Neural Repair.?2012 May;26(4):318-24. doi: 10.1177/1545968311408916. Epub 2011 Nov 15. Effects of Robot-Assisted Gait Training on Cardiopulmonary Fitness in Subacute Stroke Patients: A Randomized Controlled Study Chang WH11,?Kim MS,?Huh JP,?Lee PK,?Kim YH.
    View PubMed
  • Phys Med Biol. 2012 Apr 21;57(8):2137-50. doi: 10.1088/0031-9155/57/8/2137. Epub 2012 Mar 28. Evaluation of local electric fields generated by transcranial direct current stimulation with an extracephalic reference electrode based on realistic 3D body modeling Im CH11, Park JH, Shim M, Chang WH, Kim YH.
    View PubMed
  • Restor Neurol Neurosci.?2012;30(3):179-89. doi: 10.3233/RNN-2012-110162. rTMS with motor training modulates cortico-basal ganglia-thalamocortical circuits in stroke patients Chang WH11,?Kim YH,?Yoo WK,?Goo KH,?Park CH,?Kim ST,?Pascual-Leone A.
    View PubMed
  • Neuropsychol Rehabil.?2011 Aug;21(4):502-14. doi: 10.1080/09602011.2011.582708. Epub 2011 Jun 30. Neural correlates of donepezil-induced cognitive improvement in patients with right hemisphere stroke: A pilot study Chang WH11,?Park YH,?Ohn SH,?Park CH,?Lee PK,?Kim YH.
    View PubMed
  • Neuropediatrics. 2011 Feb;42(2):60-6. doi: 10.1055/s-0031-1279724. Epub 2011 May 24. Childhood Obesity in Ambulatory Children and Adolescents with Spastic Cerebral Palsy in Korea Park ES11, Chang WH, Park JH, Yoo JK, Kim SM, Rha DW.
    View PubMed
  • Arch Phys Med Rehabil. 2011 Jan;92(1):1-6. doi: 10.1016/j.apmr.2010.09.012. Median Nerve Conduction Study Through the Carpal Tunnel Using Segmental Nerve Length Measured by Ultrasonographic and Conventional Tape Methods Rha DW11, Im SH, Kim SK, Chang WH, Kim KJ, Lee SC.
    View PubMed
  • J Back Musculoskelet Rehabil.?2011;24(1):31-8. doi: 10.3233/BMR-2011-0272. Rapid analgesic onset of intra-articular hyaluronic acid with ketorolac in osteoarthritis of the knee Lee SC11,?Rha DW,?Chang WH.
    View PubMed
  • J Rehabil Med.?2010 Sep;42(8):758-64. doi: 10.2340/16501977-0590. LONG-TERM EFFECTS OF rTMS ON MOTOR RECOVERY IN PATIENTS AFTER SUBACUTE STROKE Chang WH11,?Kim YH,?Bang OY,?Kim ST,?Park YH,?Lee PK.
    View PubMed
  • Neuropediatrics.?2009 Dec;40(6):298-300. doi: 10.1055/s-0030-1252050. Epub 2010 May 5. Detection of Focal Cerebral Injury using Diffusion Tensor Magnetic Resonance imaging in a Boy with Becker Muscular Dystrophy Rha DW11,?Park ES,?Kim J,?Kim SH,?Chang WH.
    View PubMed
  • Neuropediatrics.?2009 Dec;40(6):269-74. doi: 10.1055/s-0030-1252049. Epub 2010 May 5. The Short-Term Effects of Combined Modified Constraint-Induced Movement Therapy and Botulinum Toxin Injection for Children with Spastic Hemiplegic Cerebral Palsy Park ES11,?Rha DW,?Lee JD,?Yoo JK,?Chang WH.
    View PubMed
  • Neuroreport.?2009 Oct 28;20(16):1434-8. doi: 10.1097/WNR.0b013e328331483d. Double decussated ipsilateral corticospinal tract in schizencephaly Chang WH11,?Kim YB,?Ohn SH,?Park CH,?Kim ST,?Kim YH.
    View PubMed