삼성서울병원

Ko En

신경외과 최정원 교수

진료분야
악성뇌종양, 뇌교종, 전이성뇌종양, 뇌수막종, 뇌종양, 감마나이프
진료일정 04 月
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진료일정 05 月
날짜
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학력

학력
2018.02 서울대학교 대학원 의학과 박사 (뇌신경과학 전공)
2013.02 서울대학교 대학원 의학과 석사 (신경외과학 전공)
2004.02 서울대학교 의과대학 졸업

경력

경력
2022.03 ~현재 성균관대학교 의과대학 신경외과학교실 부교수,삼성서울병원 신경외과 부교수
2018.03 ~ 2022.02 성균관대학교 의과대학 신경외과학교실 조교수,삼성서울병원 신경외과 조교수
2015.03 ~ 2018.02 삼성서울병원 신경외과 진료조교수
2012.05 ~ 2015.02 서울대학교병원 신경외과 임상강사
2009.04 ~ 2012.04 제주도 서귀포의료원 신경외과 공중보건의사
2005.03 ~ 2009.02 서울대학교병원 신경외과 전공의 과정 수료
2004.03 ~ 2005.02 서울대학교병원 인턴 과정 수료
  • CANCERS 2024 10.3390/cancers16010064 Treatment Outcomes after Dose-Escalated Moderately Hypofractionated Radiotherapy for Frail Patients with High-Grade Glioma Kim, N; Shin, H; Lim, D; Nam, D; Lee, JI; Seol, HJ; Kong, DS; Choi, JW; Chong, KYH; Lee, WJ
    View PubMed
  • J NEURO-ONCOL 2023 10.1007/s11060-023-04465-6 Impact of boost sequence in concurrent chemo-radiotherapy on newly diagnosed IDH-wildtype glioblastoma multiforme Kim, N; Lee, J; Nam, D; Lee, JI; Seol, HJ; Kong, DS; Choi, JW; Chong, K; Lee, WJ; Chang, JH; Kang, SG; Moon, JH; Cho, J; Lim, D; Yoon, HI
    View PubMed
  • J KOREAN NEUROSURG S 2023 10.3340/jkns.2022.0229 Effect of Bevacizumab Treatment in Cerebral Radiation Necrosis : Investigation of Response Predictors in a Single-Center Experience Lee, SH; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI
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  • YONSEI MED J 2023 10.3349/ymj.2022.0352 Clinical Outcomes of Moderately Hypofractionated Concurrent Chemoradiotherapy for Newly Diagnosed Glioblastoma Kim, N; Lim, DH; Choi, JW; Lee, JI; Kong, DS; Nam, DH; Seol, HJ
    View PubMed
  • WORLD NEUROSURG 2022 10.1016/j.wneu.2022.10.067 Impact of Postural Changes on Sinonasal Pressure After Endoscopic Endonasal Surgery Choi, HW; Choi, JW; Seol, HJ; Nam, D; Lee, JI; Kong, DS
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  • WORLD NEUROSURG 2022 10.1016/J.WNEu.2022.04.088 Factors Associated with Acute Obstructive Hydrocephalus After Retrosigmoid Approach for Extra-Axial Cerebellopontine Angle Tumors Lee, WJ; Choi, JW; Kong, DS; Nam, D; Lee, JI; Seol, HJ
    View PubMed
  • SCI REP-UK 2022 10.1038/s41598-022-13853-3 Clinical outcomes of patients with multiple courses of radiosurgery for brain metastases from non-small cell lung cancer Lee, WJ; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI
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  • J NEUROSURG-PEDIATR 2022 10.3171/2022.1.PEDS21389 Clinicoradiological and histopathological characteristics and treatment outcomes of cerebral astroblastoma in children: a single-institution experience Jeon, C; Kim, B; Choi, JW
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  • FRONT ONCOL 2022 10.3389/fonc.2022.906162 Clinical Impact of Hydroxyapatite on the Outcome of Skull Base Reconstruction for Intraoperative High-Flow CSF Leak: A Propensity Score Matching Analysis Lee, SH; Ha, CM; Hong, SD; Choi, JW; Seol, HJ; Nam, D; Lee, JI; Kong, DS
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  • ACTA NEUROCHIR 2022 10.1007/s00701-022-05203-z Combined endoscopic endonasal and transorbital multiportal approach for complex skull base lesions involving multiple compartments Lee, WJ; Hong, SD; Woo, KI; Seol, HJ; Choi, JW; Lee, JI; Nam, DH; Kong, DS
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  • WORLD NEUROSURG 2022 10.1016/j.wneu.2021.12.074 Serum Prolactin Level to Tumor Size Ratio as a Potential Parameter for Preoperative Differentiation of Prolactinomas from Hyperprolactinemia-Causing Non-functional Pituitary Adenomas Kim, JH; Hur, KY; Hong, SD; Choi, JW; Seol, HJ; Nam, DH; Lee, JI; Kong, DS
    View PubMed
  • J NEUROSURG-PEDIATR 2022 10.3171/2021.9.PEDS21254 Outcome of endoscopic transcortical intraventricular biopsy of isolated thickened pituitary stalk lesions in children Jeon, C; Choi, JW; Kong, DS; Shin, HJ
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  • WORLD NEUROSURG 2022 10.1016/j.wneu.2021.11.003 Graded Reconstruction Strategy Using a Multilayer Technique Without Lumbar Drainage After Endoscopic Endonasal Surgery Ha, CM; Hong, SD; Choi, JW; Seol, HJ; Nam, DH; Lee, JI; Kong, DS
    View PubMed
  • WORLD NEUROSURG 2022 10.1016/j.wneu.2021.10.169 Treatment Strategy for Giant Solid Hemangioblastomas in the Posterior Fossa: A Retrospective Review of 13 Consecutive Cases Jeon, C; Choi, JW; Kong, DS; Nam, DH; Lee, JI; Seol, HJ
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  • SCI REP-UK 2022 10.1038/s41598-022-06881-6 Histopathology and surgical outcome of symptomatic treatment-related changes after gamma knife radiosurgery in patients with brain metastases Kim, JH; Choi, JW; Kong, DS; Seol, HJ; Nam, D; Ryu, JW; Kim, ST; Suh, YL; Lee, JI
    View PubMed
  • J NEUROSURG 2022 10.3171/2021.2.JNS203867 Endoscopic endonasal and transorbital approaches to petrous apex lesions Lee, WJ; Hong, SD; Woo, KI; Seol, HJ; Choi, JW; Lee, JI; Nam, DH; Kong, DS
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  • J NEURO-ONCOL 2022 10.1007/s11060-021-03930-4 Bevacizumab plus irinotecan with or without gamma knife radiosurgery after failure of concurrent chemo-radiotherapy for high-grade glioma Lee, YP; Jung, HA; Lee, MS; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI; Lee, SH
    View PubMed
  • J PERS MED 2021 10.3390/jpm11111222 Risk of Postoperative Gastrointestinal Bleeding and Its Associated Factors: A Nationwide Population-Based Study in Korea Kim, SH; Han, K; Kang, G; Lee, SW; Park, CM; Cho, J; Choi, JW; Park, SJ; Kang, M; Kim, TJ; Hong, SH; Kwon, YC; Park, J; Shin, D
    View PubMed
  • J NEURO-ONCOL 2021 10.1007/s11060-021-03774-y Early hormonal recovery following endoscopic transsphenoidal surgery for silent non-functioning pituitary adenomas with hormone dysfunction Lee1, MH; Hur, KY; Hong, SD; Seol, HJ; Choi, JW; Lee, JI; Nam, D; Kong, DS
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  • J KOREAN MED SCI 2021 10.3346/jkms.2021.36.e102 Optimal Volume of the Residual Tumor to Predict Long-term Tumor Control Using Stereotactic Radiosurgery after Facial Nerve-preserving Surgery for Vestibular Schwannomas Lee1, WJ; Lee, JI; Choi, JW; Kong, DS; Nam, DH; Cho, YS; Shin, HJ; Seol, HJ
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  • J KOREAN NEUROSURG SOC 2021 10.3340/jkns.2020.0135 Immune Checkpoint Inhibitors for Non-Small-Cell Lung Cancer with Brain Metastasis : The Role of Gamma Knife Radiosurgery Lee1, MH; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Jung, HA; Sun, JM; Lee, SH; Ahn, JS; Ahn, MJ; Park, K; Lee, JI
    View PubMed
  • STEREOT FUNCT NEUROS 2020 10.1159/000508737 Gamma Knife Radiosurgery as a Primary Treatment for Nonfunctioning Pituitary Adenoma Invading the Cavernous Sinus Lee1, WJ; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI
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  • J NEUROSURG 2020 10.3171/2019.5.JNS19222 Outcome evaluation of patients treated with fractionated Gamma Knife radiosurgery for large (> 3 cm) brain metastases a dose-escalation study Kim1, KH; Kong, DS; Cho, KR; Lee, MH; Choi, JW; Seol, HJ; Kim, ST; Nam, DH; Lee, JI
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  • ACTA NEUROCHIR 2020 10.1007/s00701-020-04575-4 Stereotactic radiosurgery for orbital cavernous venous malformation a single center's experience for 15 years Lee1, WJ; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, D; Kim, YD; Woo, KI; Lee, JI
    View PubMed
  • CLIN NEUROL NEUROSUR 2020 10.1016/j.clineuro.2020.105847 Two-staged gamma knife radiosurgery for treatment of numerous (> 10) brain metastases Kim1, M; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI
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  • CANCER MED 2020 10.1002/cam4.3370 Ethnic delineation of primary glioblastoma genome Koo1, H; Choi, SW; Cho, HJ; Lee, IH; Kong, DS; Seol, HJ; Lee, JI; Choi, JW; Sa, JK; Nam, DH
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  • J NEUROSURG 2020 10.3171/2019.3.JNS183130 Volumetric changes of intracranial metastases during the course of fractionated stereotactic radiosurgery and significance of adaptive planning Lee1, MH; Kim, KH; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI
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  • J CLIN NEUROSCI 2020 10.1016/j.jocn.2020.04.047 Pattern of disease progression following stereotactic radiosurgery in malignant glioma patients Choi1, SW; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI
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  • NAT COMMUN 2020 10.1038/s41467-020-16164-1 Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma Kim1, N; Kim, HK; Lee, K; Hong, Y; Cho, JH; Choi, JW; Lee, J; Suh, YL; Ku, BM; Eum, HH; Choi, S; Choi, YL; Joung, JG; Park, WY; Jung, HA; Sun, JM; Lee, SN; Ahn, JS; Park, K; Ahn, MJ; Lee, HO
    View PubMed
  • WORLD NEUROSURG 2020 10.1016/j.wneu.2019.12.072 Postoperative Symptomatic Cerebral Infarction in Pediatric Moyamoya Disease: Risk Factors and Clinical Outcome Choi1, JW; Chong, S; Phi, JH; Lee, JY; Kim, HS; Chae, JH; Lee, J; Kim, SK
    View PubMed
  • CANCER RES TREAT 2020 10.4143/crt.2019.036 Clinical Targeted Next-Generation Sequencing Panels for Detection of Somatic Variants in Gliomas Shin1, H; Sa, JK; Bae, JS; Koo, H; Jin, S; Cho, HJ; Choi, SW; Kyoung, JM; Kim, JY; Seo, YJ; Joung, JG; Kim, NKD; Son, DS; Chung, J; Lee, T; Kong, DS; Choi, JW; Seol, HJ; Lee, JI; Suh, YL; Park, WY; Nam, DH
    View PubMed
  • WORLD NEUROSURG 2019 10.1016/j.wneu.2019.08.031 Clinical Efficacy of Optical Coherence Tomography to Predict the Visual Outcome After Endoscopic Endonasal Surgery for Suprasellar Tumors Jeon1, C; Park, KA; Hong, SD; Choi, JW; Seol, HJ; Nam, DH; Lee, JI; Shin, HJ; Kong, DS
    View PubMed
  • J NEURO-ONCOL 2019 10.1007/s11060-019-03328-3 Fractionated stereotactic radiosurgery for malignant gliomas: comparison with single session stereotactic radiosurgery Choi1, SW; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI
    View PubMed
  • EXP MOL MED 2019 10.1038/s12276-019-0351-y Secretome analysis of patient-derived GBM tumor spheres identifies midkine as a potent therapeutic target Han1, S; Shin, H; Lee, JK; Liu, ZQ; Rabadan, R; Lee, J; Shin, J; Lee, C; Yang, H; Kim, D; Kim, SH; Kim, J; Oh, JW; Kong, DS; Lee, JI; Seol, HJ; Choi, JW; Kang, HJ; Nam, DH
    View PubMed
  • STROKE 2019 10.1161/STROKEAHA.119.025609 Long-Term Outcomes of Indirect Bypass for 629 Children With Moyamoya Disease Longitudinal and Cross-Sectional Analysis Ha1, EJ; Kim, KH; Wang, KC; Phi, JH; Lee, JY; Choi, JW; Cho, BK; Yang, J; Byun, YH; Kim, SK
    View PubMed
  • NEUROSURG REV 2019 10.1007/s10143-019-01213-1 Comparison between retrosigmoid and translabyrinthine approaches for large vestibular schwannoma: focus on cerebellar injury and morbidities Kim1, KH; Cho, YS; Seol, HJ; Cho, KR; Choi, JW; Kong, DS; Shin, HJ; Nam, DH; Lee, JI
    View PubMed
  • J NEUROSURG 2019 10.3171/2018.6.JNS181099 Endoscopic transorbital surgery for Meckel's cave and middle cranial fossa tumors: surgical technique and early results Jeon1, C; Hong, CK; Woo, KI; Hong, SD; Nam, DH; Lee, JI; Choi, JW; Seol, HJ; Kong, DS
    View PubMed
  • WORLD NEUROSURG 2019 10.1016/j.wneu.2019.06.103 Preservation of the Arachnoid Membrane During Encephaloduroarteriosynangiosis Reduces Postoperative Complications without Undermining the Surgical Outcome in Pediatric Moyamoya Disease Byun1, YH; Phi, JH; Lee, JY; Ha, EJ; Kim, KH; Yang, J; Kim, HS; Ryu, SK; Choi, JW; Cho, BK; Kim, SK
    View PubMed
  • J NEUROSURG 2019 10.3171/2018.3.JNS173233 Clinical and ophthalmological outcome of endoscopic transorbital surgery for cranioorbital tumors Kong1, DS; Young, SM; Hong, CK; Kim, YD; Hong, SD; Choi, JW; Seol, HJ; Lee, JI; Shin, HJ; Nam, DH; Woo, KI
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  • INT J CANCER 2019 10.1002/ijc.32054 Hypermutagenesis in untreated adult gliomas due to inherited mismatch mutations Sa1, JK; Choi, SW; Zhao, JF; Lee, Y; Zhang, J; Kong, DS; Choi, JW; Seol, HJ; Lee, JI; Iavarone, A; Rabadan, R; Nam, DH
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  • WORLD NEUROSURG 2019 10.1016/j.wneu.2019.01.157 Prediction of IDH1 Mutation Status in Glioblastoma Using Machine Learning Technique Based on Quantitative Radiomic Data Lee1, MH; Kim, J; Kim, ST; Shin, HM; You, HJ; Choi, JW; Seol, HJ; Nam, DH; Lee, JI; Kong, DS
    View PubMed
  • J NEUROSURG 2019 10.3171/2017.12.JNS171943 Clinical and radiological outcomes of proactive Gamma Knife surgery for asymptomatic meningiomas compared with the natural course without intervention Kim1, KH; Kang, SJ; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI
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  • WORLD NEUROSURG 2019 10.1016/j.wneu.2018.11.090 Endoscopic Endonasal Versus Transorbital Surgery for Middle Cranial Fossa Tumors: Comparison of Clinical Outcomes Based on Surgical Corridors Lee1, MH; Hong, SD; Woo, KI; Kim, YD; Choi, JW; Seol, HJ; Lee, JI; Shin, HJ; Nam, DH; Kong, DS
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  • J CRANIO MAXILL SURG 2019 10.1016/j.jcms.2018.10.021 Reliable manifestations of increased intracranial pressure in patients with syndromic craniosynostosis Kim1, SY; Choi, JW; Shin, HJ; Lim, SY
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  • NEURO-ONCOLOGY 2019 10.1093/neuonc/noy123 Distinct genomic profile and specific targeted drug responses in adult cerebellar glioblastoma Cho1, HJ; Zhao, JF; Jung, SW; Ladewig, E; Kong, DS; Suh, YL; Lee, Y; Kim, D; Ahn, SH; Bordyuh, M; Kang, HJ; Sa, JK; Seo, YJ; Kim, ST; Lim, DH; Dho, YS; Lee, JI; Seol, HJ; Choi, JW; Park, WY; Park, CK; Rabadan, R; Nam, DH
    View PubMed
  • ACTA NEUROCHIR 2018 10.1007/s00701-018-3726-2 The influence of histology on the response of brain metastases to gamma knife radiosurgery: a propensity score-matched study Kim1, KH; Lee, MH; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI
    View PubMed
  • J NEUROSURG 2018 10.3171/2017.5.JNS17147 Mitochondrial abnormalities related to the dysfunction of circulating endothelial colony-forming cells in moyamoya disease Choi1, JW; Son, SM; Mook-Jung, I; Moon, YJ; Lee, JY; Wang, KC; Kang, HS; Phi, JH; Choi, SA; Chong, S; Byun, J; Kim, SK
    View PubMed
  • RADIOTHER ONCOL 2018 10.1016/j.radonc.2018.09.001 Validation of a novel molecular RPA classification in glioblastoma (GBM-molRPA) treated with chemoradiation: A multi-institutional collaborative study Wee1, CW; Kim, IH; Park, CK; Kim, JW; Dho, YS; Ohka, F; Aoki, K; Motomura, K; Natsume, A; Kim, N; Suh, CO; Chang, JH; Kim, SH; Cho, WK; Lim, DH; Nam, DH; Choi, JW; Kim, IA; Kim, CY; Oh, YT; Cho, O; Chung, WK; Kim, SH; Kim, E
    View PubMed
  • ASIA-PAC J CLIN ONCO 2018 10.1111/ajco.12861 Leptomeningeal enhancement on preoperative brain MRI in patients with glioblastoma and its clinical impact Kim1, H; Lim, DH; Kim, TG; Lee, JI; Nam, DH; Seol, HJ; Kong, DS; Choi, JW; Suh, YL; Kim, ST
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  • NAT GENET 2018 10.1038/s41588-018-0209-6 Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy Lee1, JK; Liu, ZQ; Sa, JK; Shin, S; Wang, JG; Bordyuh, M; Cho, H; Elliott, O; Chu, T; Choi, SW; Rosenbloom, DIS; Lee, IH; Shin, YJ; Kang, HJ; Kim, D; Kim, SY; Sim, MH; Kim, J; Lee, T; Seo, YJ; Shin, H; Lee, M; Kim, SH; Kwon, YJ; Oh, JW; Song, M; Kim, M; Kong, DS; Choi, JW; Seol, HJ; Lee, JI; Kim, ST; Park, JO; Kim, KM; Song, SY; Lee, JW; Kim, HC; Lee, JE; Choi, MG; Seo, SW; Shim, YM; Zo, JI; Jeong, BC; Yoon, Y; Ryu, GH; Kim, NKD; Bae, JS; Park, WY; Lee, J; Verhaak, RGW; Iavarone, A; Lee, J; Rabadan, R; Nam, DH
    View PubMed
  • MED ONCOL 2018 10.1007/s12032-018-1119-2 Comparison of 1p and 19q status of glioblastoma by whole exome sequencing, array-comparative genomic hybridization, and fluorescence in situ hybridization Sim1, J; Nam, DH; Kim, Y; Lee, IH; Choi, JW; Sa, JK; Suh, YL
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  • ACTA NEUROCHIR 2017 10.1007/s00701-017-3230-0 Optimal treatment of jugular foramen schwannomas: long-term outcome of a multidisciplinary approach for a series of 29 cases in a single institute Ryu1, SM; Lee, JI; Park, K; Choi, JW; Kong, DS; Nam, DH; Jeong, HS; Cho, YS; Seol, HJ
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  • World Neurosurg. 2016 Nov;95:399-405. doi: 10.1016/j.wneu.2016.08.046. Epub 2016 Aug 24. Outcomes of Gamma Knife Radiosurgery in Combination with Crizotinib for Patients with Brain Metastasis from Non-Small Cell Lung Cancer Choi JW11, Kong DS1, Seol HJ1, Nam DH1, Yoo KH2, Sun JM2, Ahn JS2, Ahn MJ2, Park K2, Lee JI3.
    View PubMed
  • JOURNAL OF NEUROSURGERY-PEDIATRICS, JUN 2016, 17(6):717-722, DOI: 10.3171/2015.10.PEDS15537 Association between moyamoya syndrome and the RNF213 c.14576G > A variant in patients with neurofibromatosis Type 1 Phi JH1, Choi JW, Seong MW, Kim T, Moon YJ, Lee J, Koh EJ, Ryu SK, Kang TH, Bang JS
    View PubMed
  • J Korean Neurosurg Soc. 2016 May;59(3):197-203. doi: 10.3340/jkns.2016.59.3.197. Epub 2016 May 10. Craniosynostosis in Growing Children : Pathophysiological Changes and Neurosurgical Problems Choi JW11, Lim SY2, Shin HJ1.
    View PubMed
  • World Neurosurg. 2015 Dec;84(6):1752-7. doi: 10.1016/j.wneu.2015.07.045. Epub 2015 Jul 26. Effectiveness of Postoperative Gamma Knife Radiosurgery to the Tumor Bed After Resection of Brain Metastases Choi JW11, Im YS1, Kong DS1, Seol HJ1, Nam DH1, Lee JI2.
    View PubMed

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